NCT06505863Completed
Quality of Life After Transanal Total Mesorectal Excision Compared to Traditional Total Mesorectal Excision
Does Transanal Total Mesorectal Excision (taTME) Result in Better Quality of Life and Functional Outcomes Than Traditional Total Mesorectal Excision? A Retrospective Propensity Score-adjusted Cohort Study
Source: ClinicalTrials.gov · Last updated 14 Jul 2025
Brief summary (registry, in English)
The improvement in prognosis of rectal cancer through modern therapy modalities rises questions regarding quality of life (QoL) and functional outcomes. Evidence for long-term QoL and functional outcomes of transanal total mesorectal excision (taTME) is not provided in current literature. This study will compare short-term and long-term QoL and functional outcomes after taTME compared to traditional abdominal TME (laparoscopic, robotic, and open approach)
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 249 (actual)
- First submitted
- 11 Jul 2024
- Start date
- Aug 2024
- Primary completion date
- Jan 2025
- Lead sponsor
- Cantonal Hospital of St. Gallen
- Diseases
- Colorectal cancer
- NCT number
- NCT06505863
What you commit to
- Study type: Observational
- Participants enrolled: 249
- From Aug 2024 to the primary completion date, Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- discontinuity resection (no anastomosis)
Other illness
- diagnoses other than rectal cancer
- recurrent rectal cancer
- metastatic cancer
Age
- age under 18 years
Other
- partial mesorectal excision
- incomplete TNM staging information
- 30-day mortality
- lack of quality of life data
- patient decline
Who the study is looking for
- elective total mesorectal excision followed by reconstruction with anastomosis for primary rectal cancer
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cantonal Hospital of St. Gallen Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.