NCT06506513Recruiting
Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease
Targeting Myosteatosis Though Physical Exercise to Treat Metabolic Dysfunction-associated Steatotic Liver Disease
Source: ClinicalTrials.gov · Last updated 14 Jul 2026
Brief summary (registry, in English)
Muscle changes including myosteatosis are reported as highly prevalent in metabolic dysfunction-associated steatotic liver disease (MASLD). Recent studies highlighted a link between muscle fat content and liver disease severity. Conversely, MASLD histological remission though diet or metabolic surgeries is also linked to a decrease in muscle fat content. Therefore, skeletal muscle appears as a potential target to treat MASLD.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 27 Jun 2024
- Start date
- 1 Sept 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT06506513
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Sept 2025 to the primary completion date, Sept 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- severe comorbidities including active malignancies, neuromuscular degenerative diseases
Other
- contraindications to physical activity
- excessive alcohol consumption
Who the study is looking for
- confirmed MASLD at abdominal imaging
- confirmed excessive muscle lipid content at imaging
- stable weight
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cliniques universitaires Saint-Luc Coordinator of this site? Confirm its status | Brussels | Belgium | Recruiting |
| Centre d'investigation clinique en nutrition Coordinator of this site? Confirm its status | Louvain-la-Neuve | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.