NCT06508801Recruiting
Blood Flow Restriction for Optimizing Balance in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 31 Mar 2026
Brief summary (registry, in English)
This study is being done to understand how reducing blood flow (BRT) during balance-challenging strengthening exercises (instability resistance training, or IRT) can help improve symptoms of Parkinson's disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 12 Jul 2024
- Start date
- 7 Jan 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Diseases
- Parkinson disease
- NCT number
- NCT06508801
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 7 Jan 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Had surgery in the lower extremities within the past 6 months.
- Plan to have major surgery within 2 months.
Other illness
- History of cardiovascular disease, uncontrolled hypertension (blood pressure ≥140/90 mmHg), orthostatic hypotension, deep-vein thrombosis, varicose veins, or rhabdomyolysis;
- History of other neurological disorders affecting the central nervous system such as stroke, multiple sclerosis, tumors, amyotrophic lateral sclerosis or muscle disease such as muscular dystrophy, myopathy.
- History of uncontrolled diabetes, severe osteoporosis, or cognitive impairment.
- Absolute contraindications to exercise as per the American College of Sports Medicine (uncontrolled arrhythmias, third-degree heart block, recent electrocardiogram (EKG) changes, unstable angina, acute myocardial infarction, or acute congestive heart failure
Other
- Ankle branchial index ≤ 0.9 or \> 1.3.
- Body mass index above 40; such individuals are more likely to have poorer muscle function and more pain.
- Pre-menopausal and not on birth control
- Pregnant or planning to become pregnant within the course of the study
Who the study is looking for
- Males and females between the ages 40 - 85 with a diagnosis of idiopathic Parkinson's Disease (PD) consistent with the United Kingdom PD society brain bank criteria,
- in Hoehn and Yahr stage 2-4,
- a score of ≥23 on the mini-Mental Scale Examination.
Age in the registry: 40 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Health Science Center at San Antonio Coordinator of this site? Confirm its status | San Antonio | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.