NCT06510686Completed
Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD
Comparison of the Effects of Core Stabilization and Inspiratory Muscle Training on Diaphragm Activation, Inspiratory Muscle Strength, Functional Capacity, Respiratory Functions, Physical Activity and Quality of Life in Patients With COPD
Source: ClinicalTrials.gov · Last updated 5 Sept 2025
Brief summary (registry, in English)
In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the respiratory workload. This results in impaired coordination of muscle groups, leading to muscle dysfunction. Respiratory muscle dysfunction is a significant determinant of life expectancy in COPD. Additionally, respiratory muscles unable to cope with increased workloads lead to impaired respiratory functions and reduced exercise capacity. It is widely accepted that appropriate training of respiratory muscles can increase their strength, endurance, and their close relationship with lung volume capacities. Besides their role in respiration, respiratory muscles also contribute to postural function and core stabilization. Studies on respiratory muscle training in COPD have primarily focused on inspiratory muscle strength training, neglecting the core stabilization function of respiratory muscles. However, optimal gains in a muscle can only be achieved with training tailored to its functional characteristics. Therefore, a comprehensive training program should be developed considering the multifunctional nature of respiratory muscles. Studies published in healthy individuals and different patient populations demonstrate that core training can improve lung functions. The aim of this study is to compare the effects of inspiratory muscle training and core stabilization training on diaphragm activation, inspiratory muscle strength, functional capacity, respiratory functions, physical activity, and quality of life in individuals with COPD.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 3 Jul 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 3 May 2025
- Lead sponsor
- Mustafa Ertuğrul Yaşa
- Diseases
- COPD
- NCT number
- NCT06510686
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 1 Oct 2024 to the primary completion date, 3 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having undergone pulmonary surgery
Other illness
- Having a diagnosis of lung cancer, pulmonary hypertension, and heart failure
- Having any other disease that affects respiratory functions
Other
- Being a stage 4 COPD patient according to the GOLD criteria
- Being in a COPD exacerbation period
- Scoring below 24 on the Mini-Mental Test
Who the study is looking for
- Being over 18 years old
- Having a diagnosis of COPD according to the GOLD criteria and being at stage 3 or lower
- Not being in an acute exacerbation period and having at least one month since the last exacerbation
- Being able to walk independently
- Having sufficient mental capacity to understand the tasks in the study (Mini-Mental Test \>24)
- Being willing to participate in the study
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sağlık Bilimleri Üniversitesi Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.