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NCT06511193Completed

Chronicling the COPD Patient Journey and Change in COPD Symptoms, Quality of Life and Exacerbations Following Initiation of Budenoside/Glycopyrronium/Formoterol [BGF]

Chronicling the COPD Patient Journey and Change in Impact of a Single Inhaler Combination Therapy on COPD Symptoms, Quality of Life and Exacerbations Following Initiation of Budenoside/Glycopyrronium/Formoterol [BGF](CHRONICLES COPD)

Source: ClinicalTrials.gov · Last updated 24 Jun 2026

Brief summary (registry, in English)

The CHRONICLES study will investigate the change in clinical and patient reported outcomes after six-months of treatment with Budenoside/Glycopyrronium/Formoterol \[BGF\] in a real-world setting.

Status (registry)
Completed
Study type
Observational
Enrollment
152 (actual)
First submitted
16 Jul 2024
Start date
17 Sept 2024
Primary completion date
5 May 2026
Lead sponsor
AstraZeneca
Diseases
COPD
NCT number
NCT06511193

What you commit to

  • Study type: Observational
  • Participants enrolled: 152
  • From 17 Sept 2024 to the primary completion date, 5 May 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous treatment with triple fixed-dose combination therapy in 12 months prior to screening visit
  • Hospitalisation due to COPD exacerbation within the last 30 days prior to enrolment
  • Participation in an ongoing clinical interventional or observational trial for another COPD medication (or completed another trial within last 30 days of initiating BGF)
  • Previous enrolment in this study

Other illness

  • Dementia or other health issues related to memory
  • Patient self-reporting or a physician record with an active COVID-19 infection at time of enrolment or hospitalized due to COVID-19 infection in the last 60 days

Other

  • Diagnosis of asthma
  • Inability to use inhalers
  • COPD due to documented α-1 antitrypsin deficiency
  • Pregnancy or lactation period

Who the study is looking for

  • Physician diagnosis of COPD
  • COPD patients in the Best Care Network who have a CAT score \>=10
  • Age \>=35 at time of enrolment
  • Minimum 12-month recorded prior medical history for patients
  • Physician decision and patient agreement to initiate treatment with Breztri based on routine care (and in accordance with label and reimbursement criteria)
  • Ability to read English and to provide consent to inclusion in the study

Age in the registry: 35 years to 130 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Research Site
Coordinator of this site? Confirm its status
WindsorCanadaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.