NCT06511193Completed
Chronicling the COPD Patient Journey and Change in COPD Symptoms, Quality of Life and Exacerbations Following Initiation of Budenoside/Glycopyrronium/Formoterol [BGF]
Chronicling the COPD Patient Journey and Change in Impact of a Single Inhaler Combination Therapy on COPD Symptoms, Quality of Life and Exacerbations Following Initiation of Budenoside/Glycopyrronium/Formoterol [BGF](CHRONICLES COPD)
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
The CHRONICLES study will investigate the change in clinical and patient reported outcomes after six-months of treatment with Budenoside/Glycopyrronium/Formoterol \[BGF\] in a real-world setting.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 152 (actual)
- First submitted
- 16 Jul 2024
- Start date
- 17 Sept 2024
- Primary completion date
- 5 May 2026
- Lead sponsor
- AstraZeneca
- Diseases
- COPD
- NCT number
- NCT06511193
What you commit to
- Study type: Observational
- Participants enrolled: 152
- From 17 Sept 2024 to the primary completion date, 5 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous treatment with triple fixed-dose combination therapy in 12 months prior to screening visit
- Hospitalisation due to COPD exacerbation within the last 30 days prior to enrolment
- Participation in an ongoing clinical interventional or observational trial for another COPD medication (or completed another trial within last 30 days of initiating BGF)
- Previous enrolment in this study
Other illness
- Dementia or other health issues related to memory
- Patient self-reporting or a physician record with an active COVID-19 infection at time of enrolment or hospitalized due to COVID-19 infection in the last 60 days
Other
- Diagnosis of asthma
- Inability to use inhalers
- COPD due to documented α-1 antitrypsin deficiency
- Pregnancy or lactation period
Who the study is looking for
- Physician diagnosis of COPD
- COPD patients in the Best Care Network who have a CAT score \>=10
- Age \>=35 at time of enrolment
- Minimum 12-month recorded prior medical history for patients
- Physician decision and patient agreement to initiate treatment with Breztri based on routine care (and in accordance with label and reimbursement criteria)
- Ability to read English and to provide consent to inclusion in the study
Age in the registry: 35 years to 130 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Research Site Coordinator of this site? Confirm its status | Windsor | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.