NCT06511206Completed
Determination of the Optimal Nutrient Mix to Acutely Increase Plasma Ketones
Source: ClinicalTrials.gov · Last updated 4 Apr 2025
Brief summary (registry, in English)
This study will be performed to determine the optimal nutrient mix (predominantly based on medium-chain triglycerides (MCTs)) to induce a mild ketogenic state in healthy older (60-80y), overweight/obese (BMI: 25-35 kg/m2) individuals. Since the aim is to induce a mild ketogenic state, a 25g MCT-based nutrient mix, a 25g MCT-based nutrient mix + cofactors, or a non-ketogenic control will be compared.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 20 Jun 2024
- Start date
- 8 Aug 2024
- Primary completion date
- 27 Mar 2025
- Lead sponsor
- Maastricht University Medical Center
- Diseases
- Obesity
- NCT number
- NCT06511206
What you commit to
- Study type: Interventional
- Participants enrolled: 11
- From 8 Aug 2024 to the primary completion date, 27 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous enrolment in a clinical study with an investigational product during the last 3 months or as judged by the investigator which would possibly hamper our study results
- Blood donation during or within 2 months prior to the study
Other illness
- Type 2 diabetes
- Participants with active congestive heart failure and/or severe renal and or liver insufficiency
- Uncontrolled hypertension
- Significant food allergies/intolerance (seriously hampering study meals)
Lab values
- Pre-diabetes based on one or a combination of the following criteria:
- ImpairedFastingGlucose(IFG):Fasting plasma glucose ≥ 6.1mmol/l and ≤ 6.9 mmol/l.
- HbA1c of 5.7-6.4%.
Other
- Alcohol consumption of \> 3 servings per day for man and \> 2 servings per day for woman
- Unstable body weight (weight gain or loss \> 5 kg in the last 3 months)
- Participants who do not want to be informed about unexpected medical findings
Who the study is looking for
- Aged 60-80 years
- Body mass index (BMI) 25-35 kg/m2
- Stable dietary habits (no weight loss or gain \> 5 kg in the past 3 months)
- Participants are able to provide signed and dated written informed consent prior to any study specific procedures
Age in the registry: 60 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Maastricht University Coordinator of this site? Confirm its status | Maastricht | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.