NCT06512831Completed
Isoniazid Prophylaxis Based on Risk Factors of Tuberculosis in Living Kidney Transplantation Recipients
Isoniazid Prophylaxis Based on Risk Factors of Tuberculosis in Living Kidney Transplantation Recipients: A Retrospective Cohort Study
Source: ClinicalTrials.gov · Last updated 22 Jul 2024
Brief summary (registry, in English)
Tuberculosis (TB) is a major and severe opportunistic infection among solid organ transplant recipients. Chemoprophylaxis is advised for those with latent tuberculosis infection (LTBI). However, the effectiveness of an isoniazid (INH) prophylactic approach based on TB risk factors, without relying on tuberculin skin test (TST) or interferon-gamma release assay (IGRA), remains uncertain. Therefore, the investigators conducted this retrospective study to evaluate the safety and efficacy of a 6-month INH prophylaxis regimen guided by TB risk factors in kidney transplant recipients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 1348 (actual)
- First submitted
- 14 Jul 2024
- Start date
- 1 Jun 2023
- Primary completion date
- 1 Feb 2024
- Lead sponsor
- West China Hospital
- Diseases
- Tuberculosis
- NCT number
- NCT06512831
What you commit to
- Study type: Interventional
- Participants enrolled: 1348
- From 1 Jun 2023 to the primary completion date, 1 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- multiorgan transplantation
- those who had received a nine-month course of INH.
Other illness
- active TB infection
- malignancy history in the donor and recipient
- human immunodeficiency virus infection
Other
- liver cirrhosis
Who the study is looking for
- living-donor kidney transplant recipients
- receiving standard triad immunosuppressive regimen
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| West China Hospital,Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.