NCT06522191Completed
Cross Education for Upper Extremity Motor Function and Strength in Stroke
Effect of Cross Education Using Robotic Rehabilitation on Upper Extremity Motor Function and Strength in Stroke Patients
Source: ClinicalTrials.gov · Last updated 7 Aug 2025
Brief summary (registry, in English)
Stroke is the leading cause of disability and mortality worldwide. The impact of stroke on the upper extremity functions is a common and important cause of long-term disability. Indeed, six months after the stroke, a considerable amount of patients are still unable to incorporate the affected upper limb into their daily activities. On the other hand, weaknesses are also observed in the "apparently normal" ipsilateral side of the lesion due to the presence of corticospinal fibers that do not cross to the contralateral side of the medulla. This study aims to investigate the effects of cross-education (CE) using robotic rehabilitation on upper extremity motor function and strength in patients with stroke. Secondary objectives include assessing quality of life and activities of daily living. Researchers will compare CE using robotic rehabilitation to the control group (CON) that received lower extremity-focused exercises to see if CE works to enhance rehabilitation outcomes. Participants will receive 20 min, twice weekly CE (to the less affected upper limb) or CON before the RR intervention included in the PT intervention administered 5 days in a week for 5 weeks. They will be evaluated using the relevant outcomes at the beginning and the end of the study (5th week).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 26 (actual)
- First submitted
- 22 Jul 2024
- Start date
- 29 Jul 2024
- Primary completion date
- 15 Mar 2025
- Lead sponsor
- Istanbul University - Cerrahpasa
- Diseases
- Stroke
- NCT number
- NCT06522191
What you commit to
- Study type: Interventional
- Participants enrolled: 26
- From 29 Jul 2024 to the primary completion date, 15 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Botox injections of the upper extremity within 3 months before enrollment
Other illness
- Cardiovascular instability (severe, uncontrolled hypertension, coronary artery disease, etc.)
Other
- Other neurological or musculoskeletal problems that can affect upper extremity functions
- Severe upper extremity pain defined as \>7 on the Visual Analogue Scale
Who the study is looking for
- Chronic stroke more than 3 months of stroke onset
- History of first-ever unilateral ischemic or hemorrhagic stroke
- Upper extremity motor impairment; defined by an upper extremity score ≤42 on the Fugl Meyer upper extremity (FM-UE) assessment.
- No excessive spasticity in the affected arm (Modified Ashworth Scale ≤3)
- Having the ability to communicate and understand instructions (Mini-mental state examination ≥ 24)
- Being able to sit without needing any additional support and without leaning on a backrest
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.