NCT06523335Recruiting
Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction
Intermuscular Coordination as a Novel Clinical Target for Stroke Neurorehabilitation
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
The purposes of this study include: 1. \- To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2. \- To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 74 (estimated)
- First submitted
- 22 Jul 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 1 Sept 2029
- Lead sponsor
- University of Houston
- Diseases
- Stroke
- NCT number
- NCT06523335
What you commit to
- Study type: Interventional
- Planned participants: 74
- From 1 Oct 2024 to the primary completion date, 1 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- have an orthopedic disorder involving upper limbs;
- have a history of any neurologic disease;
- have any history of epilepsy of the potential participants and/or their family members;
- have an orthopedic disorder involving upper limbs;
- cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score \< 26);
- a history of another neurologic disease;
Other
- are unable to consent;
- are pregnant.
- anesthesia of joint position sense in upper limbs;
- are pregnant or have a chance that they might be (self-reported);
Who the study is looking for
- Male or female whose age range between 40 and 75
- no known neurological injuries
- male or female hemiparetic chronic stroke survivors;
- age ranging between 40-75 year;
- with single unilateral ischemic or hemorrhagic middle cerebral artery stroke;
- neurologically stable for \>6 months;
- have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted;
- without severe spasticity (Modified Ashworth (MA) \<4);
- have not received botulinum toxin on the impaired arm within 3 months.
Age in the registry: 40 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Houston Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.