NCT06528171Recruiting
Covid-19 Long Immunité IMagerie (CLIIM)
Specific Markers of Covid-long Syndrome: Identifying the Mechanisms Involved With a View to Defining Diagnostic Criteria
Source: ClinicalTrials.gov · Last updated 22 Jun 2026
Brief summary (registry, in English)
Covid-long pathology affects a large number of patients, and represents a major medical, economic and societal challenge. To date, we have no objective criterion for a definitive diagnosis, nor any predictive tool for monitoring the evolution of Covid-long. Based on recruitment from the infectious diseases department of Nice University Hospital, the investigator's team wants to conduct an innovative pathophysiological study to better define the disease and identify specific biomarkers that could subsequently be used as a diagnostic tool for Covid-long. 120 participants will be initially included for the model learning phase: 60 controls in the CL- cohort and 60 patients in the CL+ cohort. Then 80 patients (40 CL+ and 40 Cl-) will be enrolled for the model validation phase.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 29 Jul 2024
- Start date
- 6 Dec 2024
- Primary completion date
- Jun 2028
- Lead sponsor
- Centre Hospitalier Universitaire de Nice
- NCT number
- NCT06528171
What you commit to
- Study type: Interventional
- Planned participants: 200
- From 6 Dec 2024 to the primary completion date, Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of chronic fatigue syndrome diagnosed before or after Covid.
- History of progressive psychiatric pathology.
- History of acute Covid requiring admission to intensive care and mechanical ventilation.
- History of progressive psychiatric pathology.
- History of acute Covid requiring admission to intensive care and mechanical ventilation.
Other
- No social security affiliation.
- FOR CONTROL (CL-)
- No social security affiliation.
- Pregnant or breast-feeding.
Who the study is looking for
- Case definition in line with WHO Delphi process
- History of acute COVID-19, mild, moderate or severe (episode at least 3 months at the time of inclusion).
- Absence of persistent symptoms more than 3 months after first Covid symptoms (or mild not affecting daily activities).
Criteria the registry did not label
- FOR CL+ PATIENTS
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Nice Coordinator of this site? Confirm its status | Nice | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.