NCT06529861Not yet recruiting
Mechanisms Behind Microvascular Dysfunction in INOCA
Identification of Mechanisms Behind Microvascular Dysfunction in Ischemia With No Obstructive Coronary Artery Disease
Source: ClinicalTrials.gov · Last updated 31 Jul 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of the study is to identify the causes of chest pain in patients experiencing chest pain with no signs of narrowing in the coronary arteries of the heart.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 8 Jul 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 30 Oct 2027
- Lead sponsor
- Bispebjerg Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06529861
What you commit to
- Study type: Observational
- Planned participants: 60
- From 1 Oct 2024 to the primary completion date, 30 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Uncontrolled hypertension defined as blood pressure above target 140/90 for all
- The subject has a known allergy to either: norepinephrine, adenosine, ketorolac, and or ascorbic acid (vitamin C).
Lab values
- Heart failure, defined as left ventricular ejection fraction of less than 40%
Other
- Females of childbearing potential (defined as a premeno-pausal female capable of becoming pregnant). The female patient must either be postmenopausal, defined as amen-orrhea for at least 1 year, or surgically sterile
- Co-morbidity resulting in \<1 year expected survival
- Considered by the investigator, for any reason, to be an unsuitable candidate for the study.
- Unable or unwilling to exercise, e.g. due to arthritis or injury\*
- Already are regularly physically active and/or have a maximal oxygen uptake \>45 ml/kg/min
Who the study is looking for
- Only for angina patients: Have CMD, defined as myocardial bloodflow re-serve (MBFR) \< 2.5 or hyperemic myocardial blood flow (hMBF) \< 2.3ml/g/min
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Frederiksberg Hospital, Dept. of Cardiology, Building 16, Y3, Nordre Fasanvej 57, Frederiksberg, Denmark, 2000 Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.