NCT06532344Active, not recruitingPhase 1
An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
To investigate the tolerability and safety of ONO-7913 and ONO-4538 used in combination with modified FOLFIRINOX (mFFX therapy), the standard of care, as first-line treatment in patients with metastatic pancreatic cancer.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 32 (actual)
- First submitted
- 29 Jul 2024
- Start date
- 30 Jul 2021
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Ono Pharmaceutical Co., Ltd.
- Diseases
- Pancreatic cancer
- NCT number
- NCT06532344
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 32
- From 30 Jul 2021 to the primary completion date, 30 Jun 2027
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- 2\. Patients with multiple primary cancers
Other
- 1\. Patients with severe complication
Who the study is looking for
- 1\. Untreated metastatic pancreatic cancer
- 2\. Life expectancy of at least 3 months
- 3\. Patients with ECOG performance status 0 or 1
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Juntendo University Hospital Coordinator of this site? Confirm its status | Bunkyo-ku | Japan | Unknown status |
| The University of Tokyo Hospital Coordinator of this site? Confirm its status | Bunkyō-Ku | Japan | Unknown status |
| National Cancer Center Hospital Coordinator of this site? Confirm its status | Chūōku | Japan | Unknown status |
| Seirei Hamamatsu General Hospital Coordinator of this site? Confirm its status | Hamamatsu | Japan | Unknown status |
| National Cancer Center Hospital East Coordinator of this site? Confirm its status | Kashiwa-shi | Japan | Unknown status |
| The Cancer Institute Hospital ofJFCR Coordinator of this site? Confirm its status | Koto-ku | Japan | Unknown status |
| Kyorin University Hospital Coordinator of this site? Confirm its status | Mitaka-shi | Japan | Unknown status |
| Keio University Hospital Coordinator of this site? Confirm its status | Shinjuku-ku | Japan | Unknown status |
| Kanagawa Cancer Center Coordinator of this site? Confirm its status | Yokohama | Japan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.