NCT06535113Recruiting
Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia
Source: ClinicalTrials.gov · Last updated 8 Jun 2026
Brief summary (registry, in English)
The study is designed as a collection of biological samples of newly diagnosed acute myeloid leukemia (AML) patients treated in the clinical units involved. Samples of peripheral blood (PB) and bone marrow (BM) will be analyzed to determine the Inflammasome profile before and after a first-line chemotherapy treatment.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 29 Jul 2024
- Start date
- 22 Feb 2025
- Primary completion date
- 11 May 2026
- Lead sponsor
- Ciceri Fabio
- Diseases
- Acute myeloid leukemia
- NCT number
- NCT06535113
What you commit to
- Study type: Observational
- Planned participants: 80
- From 22 Feb 2025 to the primary completion date, 11 May 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Pediatric patients (\<18 years old),
Other
- Patients unable or unwilling to sign the informed consent.
Who the study is looking for
- Any gender,
- Adults (\>18 years old),
- New suspect diagnosis of acute myeloid leukemia (ELN2022 Criteria)
- Capable of comprehend the study and the consent form,
- Willing to sign the informed consent for the study.
- For the retrospective population we will select:
- biological samples (BM Biopsies, BM Aspirates and PB) already banked upon research purpose informed consent and collected from the 01/06/2006 up to 01/06/2024 from adults patients with diagnosis of acute myeloid leukemia according to ELN2017 Criteria.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS Ospedale San Raffaele Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| GOM Bianchi Melacrino Morelli Coordinator of this site? Confirm its status | Reggio Calabria | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.