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NCT06537128Active, not recruiting

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety: Development and Evaluation of Learning to Understand and Navigate Anxiety-Adolescent

Source: ClinicalTrials.gov · Last updated 2 Oct 2026

Brief summary (registry, in English)

Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost, practicalities of attending in-person treatment sessions, and a shortage of trained providers, especially in rural areas. The goal of this project is to increase access to care for families of autistic adolescents with anxiety through an internet-based treatment model.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
139 (estimated)
First submitted
31 Jul 2024
Start date
1 Nov 2024
Primary completion date
31 Mar 2026
Lead sponsor
Baylor College of Medicine
Diseases
Autism
NCT number
NCT06537128

What you commit to

  • Study type: Interventional
  • Planned participants: 139
  • From 1 Nov 2024 to the primary completion date, 31 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • The child is receiving concurrent psychotherapy (including certain forms of social skills training, or behavioral interventions that target anxiety such as applied behavioral analysis).
  • The child has initiated new antidepressant medication within 12-weeks of assessment (4-weeks for stimulants/benzodiazepines/antipsychotics) or during therapy.
  • The child has changed psychotropic medication dosage within 4-weeks of assessment (2-weeks for stimulants/benzodiazepines/antipsychotics) or during therapy.

Other illness

  • The child has a diagnosis of a lifetime psychotic disorder and/or conduct disorder.

Other

  • The child has significant, current suicidal/homicidal ideation and/or self-injury requiring medical intervention.
  • The child has limited verbal communication abilities (e.g., no independent verbal communication),
  • The child requires a higher level than can be provided through the study (e.g., significant, current suicidal ideation)

Who the study is looking for

  • The child is between the age of 11-17 years old at enrollment.
  • The child is diagnosed with autism using a validated assessment (e.g., Autism Diagnostic Observation Schedule-Second Edition (ADOS-2), Childhood Autism Rating Scale-Second Edition (CARS-2), etc.).
  • The child has current, clinically significant anxiety and/or OCD as indicated by a clinician-administered standardized assessment (e.g. Mini-International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) and Pediatric Rating Anxiety Scale modified for autism (PARS-ASD)).
  • Anxiety disorder is the child's primary/co-primary psychiatric diagnosis, and if secondary psychopathology is present, it will not interfere with treatment.
  • One parent/guardian over the age of 18 is able and willing to participate in assessment and treatment (e.g. has sufficient English/Spanish fluency, the decisional capacity to participate, and can commit to treatment duration).
  • The child is able to communicate verbally.
  • Participants are located in Texas.
  • The participant has an IQ above 69, based on the Kaufman Brief Intelligence Test-Second Edition (KBIT-2), another valid test or clinician judgement (e.g., a previous assessment conducted, and report shared with study team)

Age in the registry: 11 years to 17 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Baylor College of Medicine
Coordinator of this site? Confirm its status
HoustonUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.