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NCT06538207CompletedPhase 1

An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Modified FOLFIRINOX (mFFX) or Gemcitabine Plus Nab-paclitaxel (GnP) Therapy as First-line Treatment in Patients With Metastatic Pancreatic Cancer

Source: ClinicalTrials.gov · Last updated 6 Feb 2025

Brief summary (registry, in English)

This study is a multicenter, open-label, uncontrolled study to investigate the tolerability and safety of ONO-4578, ONO-4538, and standard of care in combination as first-line treatment in patients with metastatic pancreatic cancer.

Status (registry)
Completed
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
46 (actual)
First submitted
29 Jul 2024
Start date
13 Jan 2021
Primary completion date
1 Oct 2024
Lead sponsor
Ono Pharmaceutical Co., Ltd.
NCT number
NCT06538207

What you commit to

  • Study type: Interventional · Phase 1
  • Participants enrolled: 46
  • From 13 Jan 2021 to the primary completion date, 1 Oct 2024
  • 9 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • 2\. Patients with multiple primary cancers

Other

  • 1\. Patients with severe complication

Who the study is looking for

  • 1\. Pancreatic invasive ducatal adenocarcinoma
  • 2\. Life expectancy of at least 3 months
  • 3\. Patients with ECOG performance status 0 or 1

Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (9)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Juntendo University Hospital
Coordinator of this site? Confirm its status
Bunkyo-kuJapanUnknown status
The University of Tokyo Hospital
Coordinator of this site? Confirm its status
Bunkyō-KuJapanUnknown status
National Cancer Center Hospital
Coordinator of this site? Confirm its status
Chuo KuJapanUnknown status
Seirei Hamamatsu General Hospital
Coordinator of this site? Confirm its status
HamamatsuJapanUnknown status
National Cancer Center Hospital East
Coordinator of this site? Confirm its status
Kashiwa-shiJapanUnknown status
The Cancer Institute Hospital of JFCR
Coordinator of this site? Confirm its status
Koto-kuJapanUnknown status
Kyorin University Hospital
Coordinator of this site? Confirm its status
Mitaka-shiJapanUnknown status
Keio University Hospital
Coordinator of this site? Confirm its status
Shinjuku-kuJapanUnknown status
Kanagawa Cancer Center
Coordinator of this site? Confirm its status
YokohamaJapanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.