NCT06540989RecruitingEarly phase 1
Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease
Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 15 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to learn whether noise-augmented feedback using automatic speech recognition improves intelligibility and social participation in individuals with Parkinson's disease. The main questions the investigators will address are: Does noise-augmented feedback lead to increased intelligibility, as measured by transcription accuracy scores? Does a self-managed speech protocol lead to increased social participation, as measured by the Communicative Participation Item Bank and the Communicative Effectiveness Index questionnaires? Participants will: Receive 2-4 initial speech assessments in-person in our lab. Engage in speech treatment sessions at home using their phone and computer four days a week for four weeks. Four of those sessions will be directly monitored online by a speech-language pathologist. The rest of the sessions are completed by the participant. Come to the lab for two post-treatment assessments following completion of treatment. Come to the lab six months after treatment completion for an additional assessment.
- Status (registry)
- Recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 42 (estimated)
- First submitted
- 29 Jul 2024
- Start date
- 1 Sept 2024
- Primary completion date
- 31 Jan 2026
- Lead sponsor
- Teachers College, Columbia University
- Diseases
- Parkinson disease
- NCT number
- NCT06540989
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 42
- From 1 Sept 2024 to the primary completion date, 31 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants will be excluded from the study if they:
- Present with atypical parkinsonism at the time of screening (or other neurological condition),
- Underwent neurosurgery treatment (DBS),
- Received intensive voice-focused treatment less than three months prior to their involvement in the current study,
- Present with any speech or voice pathology that is unrelated to PD.
Who the study is looking for
- Participants will qualify for the study if:
- They are 50-80 years old,
- They have a medical diagnosis of PD,
- They are within stages I-IV of Hoehn \& Yahr Scale,
- Their antiparkinsonian medication schedule is stable,
- They present with mild to moderate dysarthria,
- They score ≥ 25 in the MMSE,
- They score ≤ 24 in the BDI-III.
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Teachers College, Columbia University Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.