NCT06543368Completed
Low-Cost Platelet-Rich Plasma for Hemarthropathy
Low-Cost Platelet-Rich Plasma Injection for the Management of Hemarthropathy
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
Orthopedic complications can be injuries or diseases that affect the bones, muscles, and joints. Hemarthropathy is due to bleeding disorders, most commonly hemophilia, and can result in severe issues related to chronic amounts of blood in the body's joints. This causes swelling, pain, and loss of joint function. A serious barrier to treating many patients with bleeding disorders creates higher health risks and costs. Platelet-rich plasma (PRP) injection is a method that can reduce the cost of care while still offering a similar standard of care for patients. This study intends to show that low-cost PRP can be done safely in patients with bleeding disorders, without the need for expensive equipment, while monitoring patient treatment results. Study participants will receive injections for joint conditions. Being in the study requires attending 1 to 2 in-person visits at the study clinic. Participants will also complete surveys using email, text messages, in person, and/or on the phone. Participation lasts about 6 months.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 14 (actual)
- First submitted
- 29 Jul 2024
- Start date
- 23 Jul 2024
- Primary completion date
- 5 May 2025
- Lead sponsor
- University of Utah
- Diseases
- Haemophilia
- NCT number
- NCT06543368
What you commit to
- Study type: Interventional
- Participants enrolled: 14
- From 23 Jul 2024 to the primary completion date, 5 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Exclusion criteria will include recent (last two years) surgery to the affected joint, prior joint replacement.
- Prior orthobiologic injection into the affected joint.
- Inability to receive factor prior to PRP injection.
- Recent (six month) or current corticosteroid injection/intake.
- Patients with hemarthropathy in multiple joints will be eligible for up to 2 joints if multiple fit the criteria.
Other illness
- Active systemic or local infection at the site of injection,
Other
- Thrombocytopenia
- Non-ambulatory patients
- Body mass index (BMI) over 50
Who the study is looking for
- Patients of any adult age with symptomatic hemarthropathy of the ankle, knee, or elbow, based on radiographs within the last 24 months.
- Patients must have failed at least six weeks of conventional conservative treatments (such as medication or physical therapy).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.