NCT06545708Recruiting
Music Perception in SeLECTs
Music and Cognitive Deficits in Self-Limited Epilepsy with Centrotemporal Spikes
Source: ClinicalTrials.gov · Last updated 9 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years. SeLECTS is associated in 15 to 30% of patients with specific cognitive deficits, including in particular disorders in language, visuo-spatial memory, declarative memory, and attention. SeLECTS has the potential to evolve into Landau-Kleffner syndrome, the most extreme form of SeLECTS including symptoms of auditory agnosia and aphasia, with potential risks of persistent neuropsychological impairments. In a recent study in adults who had suffered Landau-Kleffner syndrome during childhood, the investigators have shown that these patients, in addition to their known deficit in verbal short-term memory, also exhibit persistent musical difficulties during adulthood, with in particular deficit in melody and rhythm short-term memory. In the present project, the investigators intend to enlarge the understanding of cognitive deficits generated by SeLECTS in children by investigating the integrity of music perception, both for melody and rhythm. To date, data about music perception in children with epilepsy are scarce and we do not know how distinct components of melody and rhythm perception and memory may be altered.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 10 Jul 2024
- Start date
- 13 Nov 2024
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Epilepsy
- NCT number
- NCT06545708
What you commit to
- Study type: Observational
- Planned participants: 100
- From 13 Nov 2024 to the primary completion date, 30 Nov 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Major cognitive impairment or inability to understand and apply instructions
Other
- Individuals refusing to participate in the study
- Pregnant or breastfeeding minors
Who the study is looking for
- Subject aged between 5 and 14 years old
- Non-opposition of parents or guardians for the child's participation in the study
- No major cognitive impairment and ability to understand and apply instructions
- Subject affiliated to a social security scheme
- Subject motivated to participate in the project
- Proficiency with the French language
- For the group of control participants:
- Without neurological or psychiatric history
- For the group of participants with seizure disorder:
- No neurological (except EPCT) or psychiatric history
- Diagnosis of self-limited epilepsy with centro-temporal spikes (PTSE) by a qualified healthcare professional.
Age in the registry: 5 years to 14 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospices Civils de Lyon Coordinator of this site? Confirm its status | Bron | France | Recruiting |
| Centre Hospitalier Le Vinatier (Bât. 452), Coordinator of this site? Confirm its status | Bron | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.