NCT06545786Recruiting
Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis
Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic (IDEA Network)
Source: ClinicalTrials.gov · Last updated 8 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients. These disorders can affect cognitive functions for years, deteriorating quality of life and increasing hospital stays and medical costs. Diagnosing PND is challenging due to their varied manifestations, such as memory and attention problems, and the lack of standardized criteria and biomarkers. One well-studied form of PND is postoperative delirium (POD). According to the ICD-10, POD is an organic cerebral syndrome characterized by disturbances in consciousness, attention, perception, and other cognitive functions. Researchers suggest that POD development involves a combination of predisposing and precipitating factors. Electroencephalography (EEG) has been used in anesthesiology to assess anesthesia depth and intraoperative awareness. Modern EEG analysis methods, like spectral analysis, offer new ways to evaluate patients' neurophysiological states. Studies show that EEG monitoring can predict complications such as intraoperative stroke and delirium, particularly in cardiothoracic and neurosurgical operations. The relationship between EEG patterns and POD is not well understood. Specific EEG patterns may indicate the risk of POD, aiding in the identification of risk factors and prevention methods. This could help anesthesiologists and surgeons optimize their approaches, reducing the risk of cognitive complications.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 265 (estimated)
- First submitted
- 6 Aug 2024
- Start date
- 25 Sept 2024
- Primary completion date
- 20 Aug 2027
- Lead sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
- Diseases
- Stroke
- NCT number
- NCT06545786
What you commit to
- Study type: Observational
- Planned participants: 265
- From 25 Sept 2024 to the primary completion date, 20 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of psychotropic drugs within 1 month prior to inclusion in the study
Other illness
- History of any mental illness
- Presence of neuromuscular diseases
Other
- Preoperative MMSE score less than 20 points
- Neurosurgical procedures
- Inability to undergo preoperative testing for any reason
Who the study is looking for
- Age ≥ 18 years
- Scheduled non-cardiac surgery of intermediate or high risk
- General anesthesia using inhalational anesthetics
- Informed consent from the patient to participate in the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| City clinical hospital named after SS Yudin Coordinator of this site? Confirm its status | Moscow | Russia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.