NCT06548269Recruiting
Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)
Source: ClinicalTrials.gov · Last updated 22 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The main purpose of this study is to investigate the safety and outcomes of different treatment strategies, including best medical therapy (OAC \[oral anticoagulation\], antiplatelet \[APT\]) and left atrial appendage closure \[LAAC\] in acute ischemic stroke (AIS) patients with atrial fibrillation (AF) based on multimodal assessment from combined brain and cardiologic work-up, and to optimize secondary prevention.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 7 Aug 2024
- Start date
- 15 Nov 2024
- Primary completion date
- 31 May 2027
- Lead sponsor
- Jinan Central Hospital
- Diseases
- Stroke, Atrial fibrillation
- NCT number
- NCT06548269
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 15 Nov 2024 to the primary completion date, 31 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Pacemaker, implantable cardioverter defibrillator or implantable cardiac monitor;
- Transient AF secondary to other reversible disorders；
Other
- Left atrial appendage has been removed or post occlusion device implantation;
- Life expectancy less than 1 year;
- Patients that cannot complete subsequent follow-up (e.g. no fixed residence, overseas patients, etc.);
- Females who are pregnant or in lactation;
- Participating in other clinical trials that could confound the evaluation of the study;
- Other circumstances that the investigator considers inappropriate for participation or may pose a significant risk to patients.
Who the study is looking for
- Age \> 18 years old；
- Acute ischemic stroke with onset ≤ 14 days；
- Previously or during this hospitalization diagnosed with non-valvular atrial fibrillation;
- Informed consent obtained from the patient or his/her legal representative；
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jinan Central Hospital Coordinator of this site? Confirm its status | Jinan | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.