NCT06550102Recruiting
Drug Response Profiling (DRP) Registry Zurich for Hematological Malignancies
Source: ClinicalTrials.gov · Last updated 15 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study is a prospective, non-randomized feasibility study of drug response profiling (DRP) in pediatric blood cancers. Primary cancer cells are isolated from patients and screened ex vivo at single-cell resolution using automated fluorescence microscopy. Drug sensitivity fingerprints are integrated with genetic annotations to inform the treating physician about personalized treatment options. The study aims to determine the practicability of real-time drug response profiling and its actionability in identifying patient-specific cancer dependencies in refractory disease settings.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 8 Aug 2024
- Start date
- 4 Jan 2022
- Primary completion date
- 31 Dec 2031
- Lead sponsor
- University Children's Hospital, Zurich
- NCT number
- NCT06550102
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 4 Jan 2022 to the primary completion date, 31 Dec 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Missing informed consent for the registry or of a clinical trial which includes DRP as add-on research
Who the study is looking for
- Pediatric and adult patients below the age of 40 years
- Diagnosis of hematological malignancy (primary, relapsed or refractory) including leukemia, myeloma or lymphoma
- Tumor material collected as part of routine diagnostics and willingness to donate tumor material for translational research
- Patient and/or guardian has signed the informed consent of the DRP registry or of a clinical trial which includes DRP as add-on research.
Age in the registry: - to 40 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Children's Hospital Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.