NCT06553391Completed
Heart Rhythm Changes in Patients With Atrial Fibrillation After Cardiopulmonary Bypass: a Retrospective Analysis
Source: ClinicalTrials.gov · Last updated 22 Aug 2025
Brief summary (registry, in English)
The goal of this observational study is to learn about the lthe effect of the tetralogy of medication regimen on intraoperative cardioversion in patients with persistent AF. The main question it aims to answer is: Does the regimen improve the success rate of cardioversion in patients with persistent AF during cardiac surgery? The treatment protocol commences with the administration of amiodarone, followed by the administration of either all or a portion of the subsequent medications: aminophylline, ephedrine, and isoproterenol. This observational cohort study was conducted at the Chinese Academy of Medical Sciences Fuwai Shenzhen Hospital using the electronic medical record database, from August 1, 2024, to January 1, 2025. Patients diagnosed with atrial fibrillation who underwent cardiac surgery between June 1, 2020, and December 31, 2024, were included in the study.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 106 (actual)
- First submitted
- 12 Jul 2024
- Start date
- Aug 2024
- Primary completion date
- Jan 2025
- Lead sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT06553391
What you commit to
- Study type: Observational
- Participants enrolled: 106
- From Aug 2024 to the primary completion date, Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergic to iodine, amiodarone or its excipients
- Patients with sick sinus syndrome, severe bradycardia (heart rate \<50bpm), second- or higher-degree atrioventricular block
Other
- Pulmonary fibrosis
- Keratopathy or severe loss of vision or blindness
- Preoperative intravenous infusion of amiodarone
- Intraoperative radiofrequency ablation of atrial fibrillation
- The patient is participating in another interventional clinical study.
Who the study is looking for
- ASA Ⅱ-Ⅲ,
- Aged 18-70 years,
- Who were scheduled for elective cardiac surgery under general anesthesia,
- Who were diagnosed with atrial fibrillation by preoperative 12-lead electrocardiogram or 24-hour holter electrocardiogram.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen Coordinator of this site? Confirm its status | Shenzhen | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.