NCT06553482Not yet recruiting
FatMax Training on Metabolic and Epigenetic Parameters
Impact of Exercise Training at Maximal Fat Oxidation (FatMax) Intensity on Metabolic and Epigenetic Parameters in Subjects With Excessive Body Mass: Study Protocol of a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 15 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Exercise is an essential pillar for the health of all individuals, as it contributes to physical, mental, and emotional well-being. Various international organizations, such as the World Health Organization, advocate for the integration of exercise into healthy lifestyles, recognizing its im-portance in disease prevention and improving quality of life. However, despite the general consensus on its value, there is no universal agreement on specific prescriptions for vulnerable groups, highlighting the need for personalized approaches that consider the unique characteristics and needs of each individual. It has been proposed that a moderate aerobic exercise training program could promote positive outcomes in individuals living with overweight and obesity, particularly with an emphasis on reducing injury risk, ensuring high adherence, and achieving favorable health changes. In this regard, the present protocol establishes the basis for a randomized clinical trial based on exercise prescription at the maximal fat oxidation rate in young individuals with overweight and obesity, with a duration of 16 weeks. Throughout the study, biochemical changes (cholesterol, glucose, triglycerides, and inflammatory markers), metabolic changes (de-termination of fat and carbohydrate utilization rates during rest and exercise), and epigenetic changes (focusing on microRNAs associated with adipogenesis, inflammation, and fat metabolism) will be monitored.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 156 (estimated)
- First submitted
- 11 Aug 2024
- Start date
- 1 Jan 2025
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Universidad Autonoma de Baja California
- Diseases
- Obesity
- NCT number
- NCT06553482
What you commit to
- Study type: Interventional
- Planned participants: 156
- From 1 Jan 2025 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Both genders
- Daily energy expenditure \<4 METs
- Body mass index ≥25 kg/m2
- Acceptance of informed consent
- Exclusion/elimination Criteria:
- ≥100 ml of alcohol consumption per week
- Consume a dietary supplement or pharmacological treatment
- Have limitations to perform regular physical activity
- Have a chronic non-communicable disease
- Answer "yes" to any of the questions on the Physical Activity Readiness- Questionnaire for Everyone (PAR-Q+); which represents a health risk.
- \<80% attendance at exercise sessions
Age in the registry: 18 years to 35 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical and Psychology School Coordinator of this site? Confirm its status | Tijuana | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.