NCT06555497CompletedEarly phase 1
Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis
A Pilot Study of Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Mild-moderate Plaque-type Psoriasis
Source: ClinicalTrials.gov · Last updated 16 Aug 2024
Brief summary (registry, in English)
A pilot study on the formulation of topical methotrexate was conducted. Patients after baseline evaluation were randomly placed into either topical 1% methotrexate gel or clobetasol propionate 0.05% ointment which was applied for 6 weeks. PASI score was assessed at two-week intervals for a total of eight weeks. Blood chemistry parameters, whole abdomen ultrasound, and adverse drug reactions while on treatment and after eight weeks were monitored as secondary outcome measures.
- Status (registry)
- Completed
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 2 (actual)
- First submitted
- 7 Aug 2024
- Start date
- 1 Jan 2022
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium
- Diseases
- Psoriasis
- NCT number
- NCT06555497
What you commit to
- Study type: Interventional · Early phase 1
- Participants enrolled: 2
- From 1 Jan 2022 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- administration of topical, systemic, or intralesional therapy or UV radiation therapy for at least 2 weeks before the study.
Lab values
- Patients with deranged laboratory results at the baseline of the study, minors or lactating mothers
Other
- patients with psoriatic lesions on the face and/or scalp,
- patients planning a pregnancy with their spouses/partners in the next three months.
Who the study is looking for
- patients with stable mild-moderate plaque psoriasis, regardless of chronicity of the disease,
- involving less than 30% of the body surface area (BSA)
- negative pregnancy test for female participants of reproductive age
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium Coordinator of this site? Confirm its status | Caloocan | Philippines | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.