NCT06555939Recruiting
Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease
Source: ClinicalTrials.gov · Last updated 5 May 2026
Brief summary (registry, in English)
Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a resilience-promoting intervention through a Collaborative Care Model. The primary goal is to determine with the resilience intervention (PRISM) is feasible and acceptable for adolescents and young adults with SCD. Exploratory outcomes include whether this intervention improves depression, anxiety, and pain interference.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 13 Aug 2024
- Start date
- 23 Oct 2025
- Primary completion date
- Sept 2029
- Lead sponsor
- Boston Children's Hospital
- Diseases
- Sickle cell disease
- NCT number
- NCT06555939
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 23 Oct 2025 to the primary completion date, Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \* does not meet above criteria
Who the study is looking for
- Aged ≥ 8 and ≤ 25 years of age at baseline
- Diagnosed with Sickle Cell Disease (HbSS, HbSC, HbS-Beta Thalassemia, and other related hemoglobinopathies)
- Receiving Medical Care at the DFCI/BCH Blood Disorders Center.
- Scored \> 9 on Patient Health Questionnaire 9-item (PHQ-9) or Generalized Anxiety Disorder (GAD)
- Able to speak English or Spanish language (for PRISM sessions)
- Able to read English or Spanish language (for completion of surveys)
- Cognitively able to participate in PRISM sessions and complete written questionnaires and surveys, as judged by the site investigator
- Willing and able to adhere to the study visit schedule and other protocol requirements
Age in the registry: 8 years to 25 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Boston Children's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.