NCT06556979Completed
Carotid Artery Stenosis and Ischemic Cerebrovascular Events After Radiotherapy in Patients With Head and Neck Cancer
Source: ClinicalTrials.gov · Last updated 16 Aug 2024
Brief summary (registry, in English)
The study had a cross-sectional design and included patients with HNC involving the oral cavity, pharynx, larynx, nasal cavity, or salivary glands who recieve RT. the investigators obtained information on their clinical and tumor characteristics and their treatment from the clinical records. Data on risk factors for atherosclerosis, medications used, and radiotherapy were also collected. Images were analyzed to determine the timing of development of CAS, identify significant (\>50%) CAS using the North American Symptomatic Carotid Endarterectomy Trial criteria, and calculate the total plaque score (TPS) and wall thickness. The purpose of this study was to determine the incidence of ICVE and of CAS in patients who receive radiotherapy for HNC and the risk factors for CAS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 907 (actual)
- First submitted
- 8 Aug 2024
- Start date
- Jan 2022
- Primary completion date
- Jan 2023
- Lead sponsor
- Chulabhorn Royal Academy
- Diseases
- Head and neck cancer, Stroke, Childhood cancers
- NCT number
- NCT06556979
What you commit to
- Study type: Observational
- Participants enrolled: 907
- From Jan 2022 to the primary completion date, Jan 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with lymphoma and those with previous treatment for CAS or radiotherapy for other diseases were excluded.
Who the study is looking for
- All patients underwent radiotherapy to the head and neck region between February 2011 and June 2022 with or without surgical resection and were investigated by computed tomography (CT) before and after radiotherapy.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Surgery, Chulabhorn Hospital, Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.