NCT06559033Recruiting
Determine the Frequency of Variants in the GBA/PSAP Genes in Patients With MM or MGUS
Determine the Frequency of Variants in the GBA/PSAP Genes in Patients With Multiple Myeloma (MM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)
Source: ClinicalTrials.gov · Last updated 10 Jun 2026
Brief summary (registry, in English)
No effective specific treatment is currently available for the management of Multiple Myeloma (MM) and Monoclonal Gammopathy of Undetermined Significance (MGUS). A better understanding of the pathophysiological mechanisms would make it possible to propose treatments specifically targeting the deregulated pathways.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 13 Aug 2024
- Start date
- 7 Oct 2025
- Primary completion date
- 2 Oct 2026
- Lead sponsor
- University Hospital, Rouen
- Diseases
- Multiple myeloma
- NCT number
- NCT06559033
What you commit to
- Study type: Observational
- Planned participants: 300
- From 7 Oct 2025 to the primary completion date, 2 Oct 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Person deprived of liberty by an administrative or judicial decision or person placed under court protection / sub-guardianship or guardianship
Who the study is looking for
- Major patients with multiple myeloma (MM) (defined by clonal proliferation of tumour plasma cells (\>10%), presence of a monoclonal peak in serum or urine (excluding non-secretory myeloma) and organ involvement secondary to bone marrow invasion) or with MGUS (defined as bone marrow plasmacytosis of less than 10%, associated with a monoclonal protein of less than 30g/L and no clinical involvement).
- Membership of a social security scheme
- Adult having read and understood the information letter and signed the consent form
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Henri Becquerel Coordinator of this site? Confirm its status | Rouen | France | Not yet recruiting |
| University Rouen Hospital Coordinator of this site? Confirm its status | Rouen | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.