NCT06561061CompletedPhase 2/3
Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2)
Zinc for Infection Prevention in Sickle Cell Anemia-2
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
A randomized double-blinded placebo-controlled trial of zinc to reduce the incidence of severe or invasive infections in Ugandan children with sickle cell anemia (SCA)
- Status (registry)
- Completed
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 16 Aug 2024
- Start date
- 10 Feb 2025
- Primary completion date
- 7 Nov 2025
- Lead sponsor
- Indiana University
- Diseases
- Sickle cell disease
- NCT number
- NCT06561061
What you commit to
- Study type: Interventional · Phase 2/3
- Participants enrolled: 100
- From 10 Feb 2025 to the primary completion date, 7 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known other chronic medical condition (e.g., HIV, malignancy, active clinical tuberculosis)
Lab values
- Absolute neutropenia (absolute neutrophil count \<500)
Age
- Severe malnutrition determined by impaired growth parameters as defined by WHO (weight for length/height or height for age z-score \<-3, using WHO growth standards)
Who the study is looking for
- Documented sickle cell anemia (HbSS supported by hemoglobin electrophoresis)
- Age range of 1.00-4.99 years, inclusive, at the time of enrollment
- Weight at least 5.0 kg at the time of enrollment
- Willingness to comply with all study-related treatments, evaluations, and follow-up
- Children whose parents or guardians give full written informed consent
Age in the registry: 12 months to 59 months · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jinja Hospital Coordinator of this site? Confirm its status | Jinja | Uganda | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.