NCT06563401Recruiting
Mortality and Cardiovascular Diseases in Adult-onset Type 1 Diabetes
Cardiovascular Disease, Mortality and Prognostic Factors in Adult-onset Type 1 Diabetes
Source: ClinicalTrials.gov · Last updated 3 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Scarce evidence is available for prognosis in adult-onset type 1 diabetes (T1D). The aim of this study is to investigate the risk of all-cause mortality, cause-specific mortality, and incident CVD in adult-onset T1D, as compared to type 2 diabetes with comparable age at diagnosis and population controls. We will explore potential modifiable factors including lifestyle and clinical characteristics that contribute to T1D prognosis. In addition, we will estimate the life expectancy associated with different age at T1D diagnosis as compared to population controls. This study will be based on people with diabetes recorded in Swedish National Diabetes Registers, with linkages to other nationwide registers to retrieve data on lifestyle factors, biomarkers, treatment and outcome information.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 900000 (estimated)
- First submitted
- 19 Aug 2024
- Start date
- 1 Jan 2024
- Primary completion date
- 31 May 2025
- Lead sponsor
- Karolinska Institutet
- Diseases
- Type 1 diabetes, Type 2 diabetes
- NCT number
- NCT06563401
What you commit to
- Study type: Observational
- Planned participants: 900000
- From 1 Jan 2024 to the primary completion date, 31 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- To avoid diabetes secondary to pancreatic cancer, we excluded people diagnosed with cancer in the digestive system 1 year prior to diabetes diagnosis and with pancreatic cancer as the underlying cause of death.
Who the study is looking for
- people with adult-onset (≥18 years) T1D diagnosed in 2001-2020 from the National Diabetes Register
- all T2D cases diagnosed at age ≥18 years in 2001-2020 recorded in the National Diabetes Register
- Everyone with T1D was matched by age, sex, and county to 50 population controls from the Total Population Register.
Age in the registry: 18 years to 110 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska Institute Coordinator of this site? Confirm its status | Stockholm | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.