NCT06564259Completed
Relationship Between Serum β2-Microglobulin and Infiltration of CD8+ in the Tumor Tissue of Hodgkin's Lymphoma Patients
The Relationship Between Serum Beta-2 Microglobulin (sB2M) Levels and CD8+ Cell Infiltration in Hodgkin Lymphoma Tissues: Impact on Chemotherapy Outcomes
Source: ClinicalTrials.gov · Last updated 21 Aug 2024
Brief summary (registry, in English)
In newly diagnosed Hodgkin lymphoma patients, pre-treatment Beta-2 Microglobulin (B2M) levels will be measured. A thorough baseline assessment will be performed using CT imaging, and tumor tissue samples will be collected for Immunohistochemical (IHC) analysis to quantify CD8+ cell infiltration. Patients will be closely monitored throughout their treatment, with a follow-up CT scan at the end of therapy to evaluate therapeutic response. This study aims to investigate the correlation between pre-treatment B2M levels and CD8+ immune cell infiltration in tumor tissues, assessing their potential as predictive markers for chemotherapy response.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 144 (actual)
- First submitted
- 18 Aug 2024
- Start date
- 4 Jan 2024
- Primary completion date
- 15 Aug 2024
- Lead sponsor
- Latakia University
- Diseases
- Hodgkin lymphoma, Childhood cancers
- NCT number
- NCT06564259
What you commit to
- Study type: Observational
- Participants enrolled: 144
- From 4 Jan 2024 to the primary completion date, 15 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have previously undergone treatment
Other illness
- Patients with acute or chronic infections
- Patients with renal disorders
- Individuals with autoimmune diseases
- HIV-positive patients
Who the study is looking for
- Newly diagnosed patients with Hodgkin lymphoma
- No prior history of malignancy
- Absence of primary or secondary immunodeficiencies
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tishreen University Coordinator of this site? Confirm its status | Latakia | Syria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.