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NCT06564259Completed

Relationship Between Serum β2-Microglobulin and Infiltration of CD8+ in the Tumor Tissue of Hodgkin's Lymphoma Patients

The Relationship Between Serum Beta-2 Microglobulin (sB2M) Levels and CD8+ Cell Infiltration in Hodgkin Lymphoma Tissues: Impact on Chemotherapy Outcomes

Source: ClinicalTrials.gov · Last updated 21 Aug 2024

Brief summary (registry, in English)

In newly diagnosed Hodgkin lymphoma patients, pre-treatment Beta-2 Microglobulin (B2M) levels will be measured. A thorough baseline assessment will be performed using CT imaging, and tumor tissue samples will be collected for Immunohistochemical (IHC) analysis to quantify CD8+ cell infiltration. Patients will be closely monitored throughout their treatment, with a follow-up CT scan at the end of therapy to evaluate therapeutic response. This study aims to investigate the correlation between pre-treatment B2M levels and CD8+ immune cell infiltration in tumor tissues, assessing their potential as predictive markers for chemotherapy response.

Status (registry)
Completed
Study type
Observational
Enrollment
144 (actual)
First submitted
18 Aug 2024
Start date
4 Jan 2024
Primary completion date
15 Aug 2024
Lead sponsor
Latakia University
NCT number
NCT06564259

What you commit to

  • Study type: Observational
  • Participants enrolled: 144
  • From 4 Jan 2024 to the primary completion date, 15 Aug 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients who have previously undergone treatment

Other illness

  • Patients with acute or chronic infections
  • Patients with renal disorders
  • Individuals with autoimmune diseases
  • HIV-positive patients

Who the study is looking for

  • Newly diagnosed patients with Hodgkin lymphoma
  • No prior history of malignancy
  • Absence of primary or secondary immunodeficiencies

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Tishreen University
Coordinator of this site? Confirm its status
LatakiaSyriaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.