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NCT06564792Completed

Contingency Management in HIV Care for Both Stimulant Use & ART Adherence

CoMBo Study: Contingency Management for Both HIV And Stimulant Use in Primary Care

Source: ClinicalTrials.gov · Last updated 14 Oct 2025

Brief summary (registry, in English)

Methamphetamine use and associated sequelae have been rising, and represent a major barrier to successful control of the HIV epidemic. Methamphetamine use is associated with poor adherence to antiretroviral therapy for HIV, and the investigators propose a trial of contingency management (providing incentives for behavioral change) targeting both reduced methamphetamine use and improved adherence to HIV medications. The investigators will utilize a real-time, point-of-care urine assay for both outcomes, aiming to evaluate feasibility, acceptability and preliminary effectiveness of HIV care-based contingency management. Hair levels will also be studied as a quantitative outcome for reduction in methamphetamine use.

Status (registry)
Completed
Study type
Interventional
Enrollment
37 (actual)
First submitted
19 Aug 2024
Start date
15 Sept 2023
Primary completion date
30 May 2024
Lead sponsor
University of California, San Francisco
Diseases
HIV
NCT number
NCT06564792

What you commit to

  • Study type: Interventional
  • Participants enrolled: 37
  • From 15 Sept 2023 to the primary completion date, 30 May 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Unable to provide urine testing weekly

Who the study is looking for

  • Stimulant use disorder
  • Living with HIV or risk for HIV
  • Suboptimal ART adherence (treatment or prevention)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UCSF at San Francisco General Hospital
Coordinator of this site? Confirm its status
San FranciscoUnited StatesUnknown status

Related publications

This page is information, not medical advice. Discuss any trial with your doctor.