NCT06564792Completed
Contingency Management in HIV Care for Both Stimulant Use & ART Adherence
CoMBo Study: Contingency Management for Both HIV And Stimulant Use in Primary Care
Source: ClinicalTrials.gov · Last updated 14 Oct 2025
Brief summary (registry, in English)
Methamphetamine use and associated sequelae have been rising, and represent a major barrier to successful control of the HIV epidemic. Methamphetamine use is associated with poor adherence to antiretroviral therapy for HIV, and the investigators propose a trial of contingency management (providing incentives for behavioral change) targeting both reduced methamphetamine use and improved adherence to HIV medications. The investigators will utilize a real-time, point-of-care urine assay for both outcomes, aiming to evaluate feasibility, acceptability and preliminary effectiveness of HIV care-based contingency management. Hair levels will also be studied as a quantitative outcome for reduction in methamphetamine use.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 37 (actual)
- First submitted
- 19 Aug 2024
- Start date
- 15 Sept 2023
- Primary completion date
- 30 May 2024
- Lead sponsor
- University of California, San Francisco
- Diseases
- HIV
- NCT number
- NCT06564792
What you commit to
- Study type: Interventional
- Participants enrolled: 37
- From 15 Sept 2023 to the primary completion date, 30 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Unable to provide urine testing weekly
Who the study is looking for
- Stimulant use disorder
- Living with HIV or risk for HIV
- Suboptimal ART adherence (treatment or prevention)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCSF at San Francisco General Hospital Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
Related publications
- Integrating HIV and Stimulant-Use Disorder Treatment: A Pilot Implementation Effectiveness Trial of Contingency Management in HIV Care.Clin Infect Dis · 2026 · PMID 41505433
This page is information, not medical advice. Discuss any trial with your doctor.