NCT06566404Not yet recruiting
Gene Expression Profiles and ctDNA for Risk Stratification in Patients With Melanoma
Gene Expression Profiles and ctDNA for Risk Stratification in Patients With Melanoma Eligible for Lymph Node Sentinel Biopsy (CORRESPOND): an Observational Prospective Study.
Source: ClinicalTrials.gov · Last updated 23 Sept 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims at assessing the role of MerlinTM and ctDNA in predicting the nodal status in patients with \>pT3b melanoma, therefore candidate for adjuvant therapy regardless of sentinel lymph node status.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 20 Aug 2024
- Start date
- 30 Oct 2024
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- European Institute of Oncology
- Diseases
- Melanoma
- NCT number
- NCT06566404
What you commit to
- Study type: Observational
- Planned participants: 200
- From 30 Oct 2024 to the primary completion date, 1 Jul 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- receipt of neoadjuvant therapy.
Other
- SLNB performed;
Who the study is looking for
- male or female, aged at least 18 years;
- histologically documented melanoma;
- thickness \> 2 mm (\>pT3b);
- clinical node-negative (cN0) and non-metastatic (cM0) disease at ultrasound (US) and computed tomography (CT) or positron emission tomography (PET) scan;
- known BRAF, N-ras proto-oncogene (NRAS) and tyrosine-protein kinase (c-KIT) mutational status;
- candidate to SLNB;
- consent for the provision of plasma samples for ctDNA analysis and tissue samples (at a central laboratory).
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.