NCT06571500Recruiting
Growth Hormone Resistance of Beta-cells in People With a Family History of Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 11 May 2026
Brief summary (registry, in English)
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a family history of type 2 diabetes at the University of Missouri. Our aim is to advance understanding of how growth hormone affects beta-cells and risk factors for developing type 2 diabetes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 30 (estimated)
- First submitted
- 22 Aug 2024
- Start date
- 15 Jul 2025
- Primary completion date
- 1 Sept 2028
- Lead sponsor
- University of Missouri-Columbia
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT06571500
What you commit to
- Study type: Observational
- Planned participants: 30
- From 15 Jul 2025 to the primary completion date, 1 Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)
Other illness
- Current diagnosis or history of type 1 or type 2 diabetes
- History of bariatric surgery
- History of intracranial hypertension, including papilledema, or a condition that increases the risk of developing intracranial hypertension, such as Turner Syndrome, Prader-Willi Syndrome, or renal impairment
- Current cancer or cancer that has been in remission less than 5 years
- First degree relative with type 1 diabetes diagnosis
- Evidence of significant anemia or significant end organ dysfunction (e.g., liver, kidney, heart disease)
- Alcohol use disorder, use of controlled substances, or smoking \>2 cigarettes per day
Other
- Pregnant, planning to become pregnant during the study, or breastfeeding
- Known, uncontrolled hypothyroidism
- Greater than 3% weight loss within three months of screening or engaged in regular (≥3 days per week), continuous moderate- or high-intensity exercise of ≥30 min duration
- Mentally disabled persons, prisoners, and persons with inability to grant voluntary informed consent
Who the study is looking for
- 18 to 59 years old
- body mass index ≥30.0 kg/m2 and \<45.0 kg/m2
- Additional, group-specific inclusion criteria:
- Family history of type 2 diabetes: first degree relative with type 2 diabetes
- Control group: no family history of type 2 diabetes
Age in the registry: 18 years to 59 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Missouri School of Medicine Coordinator of this site? Confirm its status | Columbia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.