NCT06574555CompletedPhase 4
Norepinephrine ED90 Bolus After Spinal Anesthesia in Cesarean Section
Determination of the 90% Effective Dose of the Initial Bolus of Norepinephrine in Elective Cesarean Section: An Up-Down Study
Source: ClinicalTrials.gov · Last updated 29 Aug 2025
Brief summary (registry, in English)
The investigators are aiming to determine what is the effective intravenous dose required of an initial bolus of norepinephrine prior to a maintenance infusion to prevent a 20% decrease in maternal blood pressure from baseline following the administration of spinal anesthesia for elective cesarean section in healthy parturients
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 25 Aug 2024
- Start date
- 1 Apr 2025
- Primary completion date
- 1 Aug 2025
- Lead sponsor
- Pontificia Universidad Catolica de Chile
- Diseases
- High blood pressure
- NCT number
- NCT06574555
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 60
- From 1 Apr 2025 to the primary completion date, 1 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Need for uterine exteriorization during surgery
Other illness
- Hypertensive disorders of pregnancy
- Cardiovascular disease
- Coagulation disorders.
Other
- Baseline systolic BP \<100 mmHg
- Height less than 145 cm or greater than 180 cm
- Weight less than 40 kg or greater than 100 kg
Who the study is looking for
- Full-term singleton pregnant patients
- ASA II or III
- Scheduled for elective cesarean section
- Age between 18 and 40 years.
Age in the registry: 18 years to 40 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Clínico Pontificia Universidad Católica de Chile Coordinator of this site? Confirm its status | Santiago | Chile | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.