NCT06576297Completed
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
Source: ClinicalTrials.gov · Last updated 17 Jul 2026
Brief summary (registry, in English)
In a randomized controlled trial, to study the utility of inspiratory muscle training (IMT) to improve functional outcomes in adults aged ≥70 years with heart failure (HF) who have been referred to palliative care for end-stage HF management. * The study team hypothesize that older HF patients will be able to use IMT safely, reliably, and effectively in a 12-week home-based training regimen. * The study team hypothesize that physical function (sit to stand, gait speed, grip strength), respiratory/pulmonary function, self-efficacy, fatigue and quality of life will increase among older HF patients randomized IMT versus those randomized to usual care.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 22 Feb 2024
- Start date
- 30 Jun 2024
- Primary completion date
- 28 Feb 2025
- Lead sponsor
- University of Pittsburgh
- Diseases
- Heart failure
- NCT number
- NCT06576297
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 30 Jun 2024 to the primary completion date, 28 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Major cardiovascular event or procedure within the prior 6 weeks.
- Chronic ETOH or drug dependency.
- We will exclude all of the following special populations:
Other illness
- HF secondary to significant uncorrected primary valvular disease (except mitral regurgitation secondary to left ventricular dysfunction). If valve replacement has been performed, the participant may not be enrolled for 12 months after this procedure.
- Dementia
- End-stage malignancy
- Severe valvular heart disease
- Psychiatric hospitalization within the last 3 months
Other
- Patients living in an institutional setting (e.g., skilled nursing home) during the intended period of this study.
- Severe COPD (FEV1\<50%), PVD, and/or Anemia
- Adults unable to consent
- Individuals who are not yet adults (infants, children, teenagers)
- Pregnant women
- Prisoners
Who the study is looking for
- Patients with Advanced Heart Failure (HFrEF or HFpEF), with NYHA class II, III, or IV despite a minimum of
- 6 weeks of treatment
- Age \>70 years
- Male and Female
- Optimal therapy according to AHA/ACC and HFSA HF guidelines
Age in the registry: 70 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.