NCT06576466Recruiting
Effect of Supplementation With Creatine on the Recovery of Ischemic Stroke
Effect of Supplementation With Creatine on the Early Recovery of Ischemic Stroke: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 8 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Stroke is a leading cause of disability and the second leading cause of death worldwide. Most strokes are ischemic, caused by acute arterial occlusion. Post-stroke treatment focuses on secondary prevention and rehabilitation, but few treatments address functional recovery. Creatine, a supplement known for improving physical performance, may aid in the recovery of stroke patients, reducing sarcopenia and improving strength among other effects. This pilot study will investigate the effectiveness of creatine supplementation in enhancing physical and functional recovery in ischemic stroke patients. The study will involve a randomized, double-blind clinical trial comparing creatine monohydrate to a placebo.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 92 (estimated)
- First submitted
- 22 Aug 2024
- Start date
- 27 Sept 2024
- Primary completion date
- 1 Feb 2027
- Lead sponsor
- Fundació d'investigació Sanitària de les Illes Balears
- Diseases
- Stroke
- NCT number
- NCT06576466
What you commit to
- Study type: Interventional
- Planned participants: 92
- From 27 Sept 2024 to the primary completion date, 1 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Moderate-severe disability prior to stroke, defined by an mRS\>2.
Other illness
- Neurological deficit due to stroke that prevents walking without help from another person. The use of support with a cane, crutch or walker is permitted.
- History of allergic reactions to creatine.
Lab values
- Severe kidney disease (GFR \<30ml/min/1.73 m2).
Other
- Unstable or severe clinical situation that prevents active rehabilitation.
- Moderate or severe dysphagia that makes therapeutic adherence difficult.
- Use of creatine supplements in the last 3 months, or use of anabolic products in the last 3 months.
- Musculoskeletal pathology that prevents assessment of muscle strength. For example: fractures, severe osteoarthritis, ligament tears or tendinopathies.
- Pregnancy or breastfeeding.
- Simultaneous participation in another clinical trial.
Who the study is looking for
- Age between 18 and 80 years
- Recent diagnosis of ischemic stroke (from 24 hours to 5 days) .
- Neurological deficit due to the stroke that affects mobility (paresis and/or ataxia) and requires motor rehabilitation.
- Ability to understand and sign the informed consent form, or failing that, have sufficient support to carry out the correct follow-up of the study.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IdISBa Coordinator of this site? Confirm its status | Palma de Mallorca | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.