NCT06580041Enrolling by invitationPhase 4
Precision Care for Major Depressive Disorder
Source: ClinicalTrials.gov · Last updated 5 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to assess whether phenotyping-guided intervention selection is superior to intervention selection without phenotyping guidance (i.e., routine clinician and patient judgment regarding treatment selection) for depression.
- Status (registry)
- Enrolling by invitation
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 28 Aug 2024
- Start date
- 12 Nov 2024
- Primary completion date
- 1 Sept 2029
- Lead sponsor
- University of California, San Francisco
- Diseases
- Depression
- NCT number
- NCT06580041
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 150
- From 12 Nov 2024 to the primary completion date, 1 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Unstable or untreated medical or psychiatric condition based on clinical assessment by investigator(s)
- In the Investigators' opinion, the subject is not capable of adhering to the protocol requirements, or the subject has a history of poor or suspected poor compliance in clinical research studies, or the subject has a history of poor or suspected poor compliance to antidepressant medication or that study participation is not in their best interest (e.g., different treatment is indicated given their clinical presentation)
Other
- Significant risk of suicidal or violent behavior as determined by clinical judgement
- Pregnant or breastfeeding or planning to become pregnant during the study
Who the study is looking for
- Participant is able to provide informed consent
- English speaker
- 18 years of age or older at time of consent
- Meets DSM-5 criteria for Major Depressive Disorder
- The subject meets eligibility criteria for at least one study phenotype as determined by assessments, imaging and/or clinical judgment.
- PHQ-8 score at baseline of \>= 10
- Scheduled for or completed intake in UCSF outpatient psychiatry
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nancy Friend Pritzker Psychiatry Building, University of California, San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.