NCT06580977Recruiting
Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
Source: ClinicalTrials.gov · Last updated 30 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease. Participants will be randomly allocated to one of two groups either performing cardiovascular training (experimental group) or stretching (control group) for twelve weeks, three times a week. The primary aim is to examine whether moderate-intense cardiovascular training (MICT) improves procedural memory formation (primary outcome) compared to stretching. Secondary outcomes include episodic memory formation, cognitive function, cardiorespiratory fitness, sleep quality, and brain-derived neurotrophic factor (BDNF) blood concentration levels.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 3 May 2024
- Start date
- Feb 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- Heidelberg University
- Diseases
- Parkinson disease
- NCT number
- NCT06580977
What you commit to
- Study type: Interventional
- Planned participants: 60
- From Feb 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant level of cognitive impairment (i.e., Montreal Cognitive Assessment \<21)
- Diagnosed psychiatric illness
- Known clinically relevant neurological, internal or orthopedic conditions besides Parkinsonism that would interfere with the exercise paradigm
Other
- Atypical Parkinsonism
- Deep brain stimulation or brain pacemaker
- Exceeding the recommended level of cardiovascular exercise for older adults (i.e., cardiovascular exercise done ≥150 min per week of moderate-intensity or ≥75 min per week of vigorous-intensity)
Who the study is looking for
- Diagnosed Parkinson's disease
- Disease stage ≤3 on the Hoehn \& Yahr scale
- Age ranging from 50 - 80 years
- Naive to the memory tasks (primary outcomes)
- Ability to stand and walk at least 10 meters independently
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Heidelberg University Coordinator of this site? Confirm its status | Heidelberg | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.