NCT06581133Not yet recruiting
Sleep Disruption Pattern - Epilepsy Monitoring Unit
Introducing a Structured Sleep Disruption Pattern to Provoke Earlier Seizures During Epilepsy Monitoring Unit Admissions
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
Epilepsy affects millions worldwide, with 40% of patients experiencing uncontrolled seizures despite medication. Comprehensive epilepsy centers recommend continuous video-electroencephalography monitoring to define seizure type and distinguish mimickers. This process, however, is resource-intensive, with lengthy hospital stays. The investigators' recent study identified a heightened association between arousals and epileptic activity in drug-resistant focal epilepsy patients. Building on these findings, the investigators aim to explore whether disrupting sleep with an alarm system triggers earlier occurrence of seizures, potentially offering insights to reduce hospital stay durations in epilepsy monitoring units.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 4 Apr 2024
- Start date
- 1 Oct 2026
- Primary completion date
- 1 Dec 2027
- Lead sponsor
- Duke University
- Diseases
- Epilepsy
- NCT number
- NCT06581133
What you commit to
- Study type: Interventional
- Planned participants: 75
- From 1 Oct 2026 to the primary completion date, 1 Dec 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- \- Multiple seizures a day based on pre-admission seizure diary
Who the study is looking for
- Age 14 to 60 years
- EMU monitoring for presurgical evaluations
- Average 2-3 seizures per week based on pre-admission seizure diary
- Sleep as a known seizure trigger
Age in the registry: 14 years to 60 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.