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NCT06581133Not yet recruiting

Sleep Disruption Pattern - Epilepsy Monitoring Unit

Introducing a Structured Sleep Disruption Pattern to Provoke Earlier Seizures During Epilepsy Monitoring Unit Admissions

Source: ClinicalTrials.gov · Last updated 8 Sept 2026

Brief summary (registry, in English)

Epilepsy affects millions worldwide, with 40% of patients experiencing uncontrolled seizures despite medication. Comprehensive epilepsy centers recommend continuous video-electroencephalography monitoring to define seizure type and distinguish mimickers. This process, however, is resource-intensive, with lengthy hospital stays. The investigators' recent study identified a heightened association between arousals and epileptic activity in drug-resistant focal epilepsy patients. Building on these findings, the investigators aim to explore whether disrupting sleep with an alarm system triggers earlier occurrence of seizures, potentially offering insights to reduce hospital stay durations in epilepsy monitoring units.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
75 (estimated)
First submitted
4 Apr 2024
Start date
1 Oct 2026
Primary completion date
1 Dec 2027
Lead sponsor
Duke University
Diseases
Epilepsy
NCT number
NCT06581133

What you commit to

  • Study type: Interventional
  • Planned participants: 75
  • From 1 Oct 2026 to the primary completion date, 1 Dec 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • \- Multiple seizures a day based on pre-admission seizure diary

Who the study is looking for

  • Age 14 to 60 years
  • EMU monitoring for presurgical evaluations
  • Average 2-3 seizures per week based on pre-admission seizure diary
  • Sleep as a known seizure trigger

Age in the registry: 14 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.