NCT06586606CompletedPhase 1
A Study to Evaluate the Effects of Itraconazole on MK-1708 in Healthy Participants (MK-1708-003)
A Two-Period Study to Evaluate the Effects of Multiple Oral Doses of Itraconazole on the Single Dose PK of MK-1708 in Healthy Participants
Source: ClinicalTrials.gov · Last updated 18 Dec 2024
Brief summary (registry, in English)
The goal of the study is to see what happens to levels of MK-1708 a person's body over time. Researchers will compare what happens to MK-1708 in the body when it is given with or without a medicine called itraconazole.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 12 (actual)
- First submitted
- 4 Sept 2024
- Start date
- 3 Oct 2024
- Primary completion date
- 10 Dec 2024
- Lead sponsor
- Merck Sharp & Dohme LLC
- Diseases
- Alzheimer disease
- NCT number
- NCT06586606
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 12
- From 3 Oct 2024 to the primary completion date, 10 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Has a history of clinically significant endocrine, gastrointestinal (GI), cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
- Has a history of cancer
Other
- The key exclusion criteria include but are not limited to the following:
Who the study is looking for
- The key inclusion criteria include but are not limited to the following:
- Is in good health before randomization
- Has a body mass index (BMI) ≥18.5 and ≤32 kg/m\^2, inclusive
Age in the registry: 18 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| QPS-MRA, LLC ( Site 0001) Coordinator of this site? Confirm its status | South Miami | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.