NCT06587165Recruiting
Quantifying New Heart Muscle Cells
A Pilot Study for Quantifying New Heart Muscle Cells
Source: ClinicalTrials.gov · Last updated 15 Jun 2026
Brief summary (registry, in English)
Regenerative therapies could provide new ways of treating heart failure. Unlike many organs in the human body, such as the skin and the GI tract, the ability to regenerate heart muscle decreases after birth, but the precise timing of this decrease and how this decrease is altered in heart disease are uncertain. The investigators will use an innovative approach to quantify cellular heart regeneration in pediatric patients, an appropriate population for determining this decline as well as the potential for reactivating heart muscle regeneration. The study has now been registered on ClinicalTrials.gov, despite its initiation on July 23, 2015, as registration was not mandated at the original study site, the University of Pittsburgh Medical Center. However, following the transfer of the study to Weill Cornell Medicine, adherence to institutional requirements necessitated its registration on ClinicalTrials.gov.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 28 Aug 2024
- Start date
- 15 May 2026
- Primary completion date
- 1 Mar 2027
- Lead sponsor
- Weill Medical College of Cornell University
- Diseases
- Heart failure
- NCT number
- NCT06587165
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 15 May 2026 to the primary completion date, 1 Mar 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with low chance of having resection of myocardium as part of their surgical care.
Who the study is looking for
- Patients at 30 days of age to 1 year of age undergoing scheduled elective cardiac surgery will be eligible for study inclusion.
- The investigators will recruit patients at 30 days of age to 1 year of age with those types of heart disease whose surgical approach has a high probability of myocardial resection.
- Diagnosis of ToF/PS or other types of heart disease that have a high likelihood of requiring surgery that involves routine resection of myocardium that becomes available for research
Age in the registry: 30 days to 1 year · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Weill Cornell Medicine Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| Columbia University (Morgan Stanley Children's Hospital) Coordinator of this site? Confirm its status | New York | United States | Not yet recruiting |
| Children's Hospital of Philadelphia Coordinator of this site? Confirm its status | Philadelphia | United States | Not yet recruiting |
| UPMC Children's Hospital of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.