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NCT06587165Recruiting

Quantifying New Heart Muscle Cells

A Pilot Study for Quantifying New Heart Muscle Cells

Source: ClinicalTrials.gov · Last updated 15 Jun 2026

Brief summary (registry, in English)

Regenerative therapies could provide new ways of treating heart failure. Unlike many organs in the human body, such as the skin and the GI tract, the ability to regenerate heart muscle decreases after birth, but the precise timing of this decrease and how this decrease is altered in heart disease are uncertain. The investigators will use an innovative approach to quantify cellular heart regeneration in pediatric patients, an appropriate population for determining this decline as well as the potential for reactivating heart muscle regeneration. The study has now been registered on ClinicalTrials.gov, despite its initiation on July 23, 2015, as registration was not mandated at the original study site, the University of Pittsburgh Medical Center. However, following the transfer of the study to Weill Cornell Medicine, adherence to institutional requirements necessitated its registration on ClinicalTrials.gov.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
30 (estimated)
First submitted
28 Aug 2024
Start date
15 May 2026
Primary completion date
1 Mar 2027
Lead sponsor
Weill Medical College of Cornell University
NCT number
NCT06587165

What you commit to

  • Study type: Interventional
  • Planned participants: 30
  • From 15 May 2026 to the primary completion date, 1 Mar 2027
  • 4 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients with low chance of having resection of myocardium as part of their surgical care.

Who the study is looking for

  • Patients at 30 days of age to 1 year of age undergoing scheduled elective cardiac surgery will be eligible for study inclusion.
  • The investigators will recruit patients at 30 days of age to 1 year of age with those types of heart disease whose surgical approach has a high probability of myocardial resection.
  • Diagnosis of ToF/PS or other types of heart disease that have a high likelihood of requiring surgery that involves routine resection of myocardium that becomes available for research

Age in the registry: 30 days to 1 year · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (4)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Weill Cornell Medicine
Coordinator of this site? Confirm its status
New YorkUnited StatesRecruiting
Columbia University (Morgan Stanley Children's Hospital)
Coordinator of this site? Confirm its status
New YorkUnited StatesNot yet recruiting
Children's Hospital of Philadelphia
Coordinator of this site? Confirm its status
PhiladelphiaUnited StatesNot yet recruiting
UPMC Children's Hospital of Pittsburgh
Coordinator of this site? Confirm its status
PittsburghUnited StatesNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.