NCT06587451CompletedPhase 3
Integrated PK/efficacy, safety, and immunogenicity study to demonstrate similarity of JPB898, a proposed biosimilar to nivolumab, to Opdivo® in combination with Yervoy®
Source: EU CTIS (euclinicaltrials.eu) · Last updated 2 Dec 2025
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 302 (actual)
- First submitted
- 25 Mar 2024
- Start date
- 28 Mar 2025
- Lead sponsor
- H e x a l AG
- Diseases
- Melanoma
- NCT number
- NCT06587451
- EU CT number
- 2023-507865-24-00
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 302
- 57 sites in 11 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study, not your situation.
Sites (57)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD Coordinator of this site? Confirm its status | Sofia | Bulgaria | Completed |
| National Oncological Medical Center EOOD Coordinator of this site? Confirm its status | Sofia | Bulgaria | Completed |
| Fakultni Nemocnice Hradec Kralove Coordinator of this site? Confirm its status | Novy Hradec Kralove | Czechia | Completed |
| Nemocnice AGEL Nový Jičín a.s. Coordinator of this site? Confirm its status | Nový Jičín | Czechia | Completed |
| Kožní ordinace Coordinator of this site? Confirm its status | Praha 1 | Czechia | Completed |
| Deutsches Rotes Kreuz Gemeinnuetzige Krankenhaus Sachsen GmbH Coordinator of this site? Confirm its status | Chemnitz | Germany | Completed |
| University Hospital Cologne AöR Coordinator of this site? Confirm its status | Cologne | Germany | Completed |
| Universitaetsklinikum Duesseldorf AöR Coordinator of this site? Confirm its status | Duesseldorf | Germany | Completed |
| SRH Wald-Klinikum Gera GmbH Coordinator of this site? Confirm its status | Gera | Germany | Completed |
| Justus-Liebig-Universitaet Giessen Coordinator of this site? Confirm its status | Giessen | Germany | Completed |
| Institut Catala d'Oncologia Coordinator of this site? Confirm its status | Badalona | Spain | Completed |
| Hospital General Universitario Reina Sofia Coordinator of this site? Confirm its status | Córdoba | Spain | Completed |
| Hospital Universitario 12 de Octubre Coordinator of this site? Confirm its status | Madrid | Spain | Completed |
| MD Anderson Cancer Center Coordinator of this site? Confirm its status | Madrid | Spain | Completed |
| Hospital Beata María Ana Coordinator of this site? Confirm its status | Madrid | Spain | Completed |
| Hospital Universitario Regional de Málaga Coordinator of this site? Confirm its status | Málaga | Spain | Completed |
| H.C. Hospitales S.L. Coordinator of this site? Confirm its status | Marbella | Spain | Completed |
| Hospital Universitario Central De Asturias Coordinator of this site? Confirm its status | Oviedo | Spain | Completed |
| University Hospital Of Canary Islands Coordinator of this site? Confirm its status | San Cristobal De La Laguna | Spain | Completed |
| Hospital Universitario Marqués de Valdecilla Coordinator of this site? Confirm its status | Santander | Spain | Completed |
| Complexo Hospitalario Universitario De Santiago Coordinator of this site? Confirm its status | Santiago de Compostela | Spain | Completed |
| Hospital Universitario Y Politecnico La Fe Coordinator of this site? Confirm its status | Valencia | Spain | Completed |
| Hospital Universitario Dr. Peset Aleixandre Coordinator of this site? Confirm its status | Valencia | Spain | Completed |
| Hospital Clinico Universitario de Valencia Coordinator of this site? Confirm its status | Valencia | Spain | Completed |
| Metropolitan Hospital Coordinator of this site? Confirm its status | Pireas | Greece | Completed |
| Athens Medical Center S.A. Coordinator of this site? Confirm its status | Thessaloniki | Greece | Completed |
| Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz Coordinator of this site? Confirm its status | Győr | Hungary | Completed |
| Istituto Tumori Bari Giovanni Paolo II Coordinator of this site? Confirm its status | Bari | Italy | Completed |
| Universita' Degli Studi G. D'annunzio Di Chieti Coordinator of this site? Confirm its status | Chieti | Italy | Completed |
| Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l Coordinator of this site? Confirm its status | Meldola | Italy | Completed |
| Azienda Ospedaliero - Universitaria di Modena Coordinator of this site? Confirm its status | Modena | Italy | Completed |
| Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli Coordinator of this site? Confirm its status | Naples | Italy | Completed |
| Azienda Ospedaliero Universitaria Pisana Coordinator of this site? Confirm its status | Pisa | Italy | Completed |
| Azienda Unità Sanitaria Locale della Romagna Coordinator of this site? Confirm its status | Ravenna | Italy | Completed |
| Fondazione Luigi Maria Monti Coordinator of this site? Confirm its status | Rome | Italy | Completed |
| Humanitas Research Hospital Coordinator of this site? Confirm its status | Rozzano | Italy | Completed |
| Azienda Ospedaliera Universitaria Senese Coordinator of this site? Confirm its status | Siena | Italy | Completed |
| Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino Coordinator of this site? Confirm its status | Turin | Italy | Completed |
| Lietuvos sveikatos mokslu universiteto ligonine Kauno klinikos Coordinator of this site? Confirm its status | Kaunas | Lithuania | Completed |
| Klaipedos universiteto ligonine VšĮ Coordinator of this site? Confirm its status | Klaipeda | Lithuania | Completed |
| Nacionalinis Vezio Institutas Coordinator of this site? Confirm its status | Vilnius | Lithuania | Completed |
| Centrum Onkologii Im. Prof. Franciszka Lukaszczyka W Bydgoszczy Coordinator of this site? Confirm its status | Bydgoszcz | Poland | Completed |
| Niepubliczny Zakład Opieki Zdrowotnej Zespół Poradni Specjalistycznych "Termedica" Coordinator of this site? Confirm its status | Poznan | Poland | Completed |
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Coordinator of this site? Confirm its status | Warsaw | Poland | Completed |
| Unidade Local De Saude De Almada-Seixal E.P.E. Coordinator of this site? Confirm its status | Almada | Portugal | Completed |
| Unidade Local de Saúde de Coimbra, E.P.E. Coordinator of this site? Confirm its status | Coimbra | Portugal | Completed |
| Hospital Cuf Tejo S.A. Coordinator of this site? Confirm its status | Lisbon | Portugal | Completed |
| Instituto Portugues de Oncologia do Porto Francisco Gentil, E.P.E. Coordinator of this site? Confirm its status | Porto | Portugal | Completed |
| Memorial Healthcare International S R L Coordinator of this site? Confirm its status | Bucharest | Romania | Completed |
| Spitalul Clinic Colțea Coordinator of this site? Confirm its status | Bucharest | Romania | Completed |
| Institutul Oncologic Prof. Dr. Alexandru Trestioreanu Bucuresti Coordinator of this site? Confirm its status | Bucharest | Romania | Completed |
| Gral Medical S.R.L Coordinator of this site? Confirm its status | Bucharest | Romania | Completed |
| Spitalul Clinic Judetean De Urgenta Cluj Coordinator of this site? Confirm its status | Cluj-Napoca | Romania | Completed |
| Medisprof S.R.L. Coordinator of this site? Confirm its status | Cluj-Napoca | Romania | Completed |
| Centrul De Oncologie SF Nectarie S.R.L. Coordinator of this site? Confirm its status | Craiova | Romania | Completed |
| Radiotherapy Center Cluj S.R.L. Coordinator of this site? Confirm its status | Floresti | Romania | Completed |
| Mnt Healthcare Europe S.R.L. Coordinator of this site? Confirm its status | Pantelimon | Romania | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.