NCT06592508Completed
Evaluation Of A Virtual Cardiology Program To Improve Outcomes After Acute Decompensated Heart Failure
Evaluation Of A Virtual Cardiology Program To Improve Outcomes After Acute Decompensated Heart Failure: The ELEVATE-HF Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate how safe and effective a remote, virtual, cardiology program is that provides heart failure education to patients, monitors for worsening heart failure, and quickly adjusts heart failure medications, compared to usual care medication use and adjustment, in participants with decompensated heart failure that are recently hospitalized.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 73 (actual)
- First submitted
- 27 Aug 2024
- Start date
- 27 Sept 2024
- Primary completion date
- 31 Mar 2026
- Lead sponsor
- Duke University
- Diseases
- Heart failure
- NCT number
- NCT06592508
What you commit to
- Study type: Interventional
- Participants enrolled: 73
- From 27 Sept 2024 to the primary completion date, 31 Mar 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Optimized or nearly optimized on evidence-based medical therapies for HF as determined by local investigator
- Chronic use of intravenous inotropic medications including milrinone, dobutamine, or dopamine
- History of prior heart transplant or currently listed for heart transplant
- Currently receiving hospice care
- Chronically resides in an assisted living or skilled nursing facility where medications are managed by facility personnel
Other illness
- Terminal illness other than HF with a life expectancy of \<1 year as determined by the enrolling clinician-investigator
Lab values
- eGFR of \<20 mL/min/1.73m2 ongoing chronic dialysis at screening. The eGFR should be estimated using the 2021 Chronic Kidney Disease Epidemiology Collaboration (2021 CKD-EPI) creatinine equation.
Other
- Current pregnancy
- Current left ventricular assist device or planned left ventricular assist device in the next 6 months
Who the study is looking for
- Age ≥18 years of age
- Acute decompensated HF as a primary cause of hospitalization. Hospitalizations for acute decompensated HF will be determined by local clinician-investigators but should include findings of acute HF (i.e., symptoms, signs, and/or laboratory/imaging abnormalities) and treatments aimed at acute HF (e.g., intravenous diuretics, vasodilators, or inotropes). Participants with a new diagnosis of HF may be enrolled. The enrollment will be monitored to ensure no more than 2/3 of the total cohort has new-onset HF.
- Fluent in written and spoken English
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Premier Health Coordinator of this site? Confirm its status | Dayton | United States | Unknown status |
| Northeast Georgia Medical Center Coordinator of this site? Confirm its status | Gainesville | United States | Unknown status |
| Cardiovascular Institute of Northwest Florida Coordinator of this site? Confirm its status | Panama City | United States | Unknown status |
| Duke Raleigh Hospital Coordinator of this site? Confirm its status | Raleigh | United States | Unknown status |
| ProMedica Toledo Hospital Coordinator of this site? Confirm its status | Toledo | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.