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NCT06592508Completed

Evaluation Of A Virtual Cardiology Program To Improve Outcomes After Acute Decompensated Heart Failure

Evaluation Of A Virtual Cardiology Program To Improve Outcomes After Acute Decompensated Heart Failure: The ELEVATE-HF Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 29 May 2026

Brief summary (registry, in English)

The purpose of this study is to evaluate how safe and effective a remote, virtual, cardiology program is that provides heart failure education to patients, monitors for worsening heart failure, and quickly adjusts heart failure medications, compared to usual care medication use and adjustment, in participants with decompensated heart failure that are recently hospitalized.

Status (registry)
Completed
Study type
Interventional
Enrollment
73 (actual)
First submitted
27 Aug 2024
Start date
27 Sept 2024
Primary completion date
31 Mar 2026
Lead sponsor
Duke University
NCT number
NCT06592508

What you commit to

  • Study type: Interventional
  • Participants enrolled: 73
  • From 27 Sept 2024 to the primary completion date, 31 Mar 2026
  • 5 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Optimized or nearly optimized on evidence-based medical therapies for HF as determined by local investigator
  • Chronic use of intravenous inotropic medications including milrinone, dobutamine, or dopamine
  • History of prior heart transplant or currently listed for heart transplant
  • Currently receiving hospice care
  • Chronically resides in an assisted living or skilled nursing facility where medications are managed by facility personnel

Other illness

  • Terminal illness other than HF with a life expectancy of \<1 year as determined by the enrolling clinician-investigator

Lab values

  • eGFR of \<20 mL/min/1.73m2 ongoing chronic dialysis at screening. The eGFR should be estimated using the 2021 Chronic Kidney Disease Epidemiology Collaboration (2021 CKD-EPI) creatinine equation.

Other

  • Current pregnancy
  • Current left ventricular assist device or planned left ventricular assist device in the next 6 months

Who the study is looking for

  • Age ≥18 years of age
  • Acute decompensated HF as a primary cause of hospitalization. Hospitalizations for acute decompensated HF will be determined by local clinician-investigators but should include findings of acute HF (i.e., symptoms, signs, and/or laboratory/imaging abnormalities) and treatments aimed at acute HF (e.g., intravenous diuretics, vasodilators, or inotropes). Participants with a new diagnosis of HF may be enrolled. The enrollment will be monitored to ensure no more than 2/3 of the total cohort has new-onset HF.
  • Fluent in written and spoken English

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Premier Health
Coordinator of this site? Confirm its status
DaytonUnited StatesUnknown status
Northeast Georgia Medical Center
Coordinator of this site? Confirm its status
GainesvilleUnited StatesUnknown status
Cardiovascular Institute of Northwest Florida
Coordinator of this site? Confirm its status
Panama CityUnited StatesUnknown status
Duke Raleigh Hospital
Coordinator of this site? Confirm its status
RaleighUnited StatesUnknown status
ProMedica Toledo Hospital
Coordinator of this site? Confirm its status
ToledoUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.