NCT06593418Not yet recruiting
Cardiac Radioablation for VT
A Phase I/II Study of Cardiac Radioablation for Refractory Ventricular Tachycardia
Source: ClinicalTrials.gov · Last updated 20 Apr 2026
Brief summary (registry, in English)
The goal of this interventional study is to determine the minimum dose necessary for successful cardiac radioablation of refractory ventricular tachycardia (VT) and to study the utility of target volume definition using Delayed Enhancement Cardiac MRI (DE-CMR) .
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 9 Sept 2024
- Start date
- Jul 2026
- Primary completion date
- Jan 2028
- Lead sponsor
- Corewell Health East
- Diseases
- Coronary artery disease
- NCT number
- NCT06593418
What you commit to
- Study type: Interventional
- Planned participants: 24
- From Jul 2026 to the primary completion date, Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior radiation therapy to the chest or upper abdomen.
Other illness
- Class IV heart failure
- Interstitial lung disease.
Other
- Abandoned leads.
Who the study is looking for
- Participants must be 18 years or older.
- Automatic implanted cardiac defibrillator present.
- VT is monomorphic with at least two episodes of VT within an eight week (56 day) period as recorded by an AICD or heart failure related to VT or VT storm.
- Ejection fraction ≥20%.
- At least one previous cardiac ablation for VT.
- VT refractory despite antiarrhythmic medications.
- Likely to live for 12 months in the absence of VT.
- AICD in a position in the chest RT to be given without direct radiation.
- Woman of reproductive age must ensure that she won't become pregnant or breastfeed at the time of RT.
- The participant has no contraindications to a Cardiac MRI as per routine Cardiology practice.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Corewell Health William Beaumont University Hospital Coordinator of this site? Confirm its status | Royal Oak | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.