NCT06596317Completed
Impact of Indigo Carmine Pump Spraying on the Adenoma Detection Rate
Impact of Indigo Carmine Pump Spraying on the Adenoma Detection Rate: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 12 Mar 2025
Brief summary (registry, in English)
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate. The traditional method of dye spraying with spraying catheter or syringe would consume a lot of time and dye volume. Now, the more convenient auxiliary water supply channel can be used to spray indigo carmine. In order to explore the clinical application value of spraying indigo carmine solution by auxiliary water channel in high-risk population, we performed a prospective, randomized controlled trial to compare adenoma detection rate of conventional colonoscopy and chromoendoscopy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 330 (actual)
- First submitted
- 12 Apr 2023
- Start date
- 11 Jan 2024
- Primary completion date
- 30 Dec 2024
- Lead sponsor
- Shandong University
- Diseases
- Colorectal cancer
- NCT number
- NCT06596317
What you commit to
- Study type: Interventional
- Participants enrolled: 330
- From 11 Jan 2024 to the primary completion date, 30 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who received urgent or therapeutic colonoscopy
- Patients with aspirin, clopidogrel or other anticoagulants/ antiplatelet drugs intake within 7 days
Other illness
- Patients with pregnancy, inflammatory bowel disease, polyposis syndromes, suspected CRC; intestinal obstruction, coagulopathy
Other
- Patients with severe comorbidity
- Patients who are not suitable for colonoscopy
- Patients with failed cecal intubation
- Patients with inadequate bowel preparation quality (Boston score ≤5)
- Patients who refuse to participate or to provide informed consent
Who the study is looking for
- Patients with a history of colorectal cancer or colorectal adenoma
- Patients whose first-degree relatives have a history of colorectal cancer or colorectal adenoma
- Patients with gastrointestinal symptoms (abdominal pain, bloody stool, chronic diarrhea or constipation, Unexplained anemia or weight loss;
- Patients with positive fecal occult blood tests
Age in the registry: 45 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Qilu Hospital of Shandong University Coordinator of this site? Confirm its status | Jinan | China | Unknown status |
Related publications
- The Efficacy of Pan-Indigo Carmine Chromoendoscopy by Water-Jet Pump in the Detection of Colorectal Lesions: A Randomized Controlled Trial.J Gastroenterol Hepatol · 2026 · PMID 42333873
This page is information, not medical advice. Discuss any trial with your doctor.