NCT06598150Recruiting
Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
Mapping Corticoreticulospinal Motor Control Using Brainstem and Spinal Cord fMRI in Chronic Hemiparetic Stroke
Source: ClinicalTrials.gov · Last updated 1 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 12 Sept 2024
- Start date
- 20 May 2023
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- Northwestern University
- Diseases
- Stroke
- NCT number
- NCT06598150
What you commit to
- Study type: Interventional
- Planned participants: 32
- From 20 May 2023 to the primary completion date, 31 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- brain radiation
- Concurrent enrollment in an intervention study
- Concurrent use of medications known to suppress central nervous system activity
Other illness
- Diagnosis/history of:
- dementia
- Parkinson's disease
Other
- MRI contraindications
- Severe claustrophobia
- Pregnant women
- Prisoners
- Vulnerable populations
- multiple sclerosis
- brain tumor
- traumatic brain injury
Who the study is looking for
- Adults aged at least 18y
- Able to perform shoulder abduction task (confirmed during screening and initial examination)
- Safe to undergo MRI
- Able to follow visual instructions using MRI-compatible vision correction goggles
- No brainstem or cerebellar lesions
- No severe concurrent medical problems
- Cognitive/attentional capacity to focus on a task
- Able to communicate in English or Spanish
- Additional inclusion criteria for stroke participants:
- Have sustained only one unilateral subcortical, ischemic lesion in the territory supplied by the Middle Cerebral Artery (confirmed by clinical or radiological reports) at least one year prior to participation in this project
- Paresis confined to one side, with moderate-to-severe motor impairment of the upper limb (Upper Extremity Fugl-Meyer score between 10 and 45).
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.