NCT06599372Recruiting
Evaluation of the Efficacy of Transcranial Magnetic Stimulation on Resistant Auditory Hallucinations in Schizophrenia
Treatment of Resistant Auditory Hallucinations in Schizophrenia by Repetitive Transcranial Magnetic Stimulation. Naturalistic Study
Source: ClinicalTrials.gov · Last updated 19 Sept 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This open naturalistic study aims to evaluate the efficacy of rTMS in routine practice on auditory resistant hallucinations (AHR) of patients with schizophrenia. To this end, two stimulation methods will be offered to patients: the rTMS stimulation method and the cTBS stimulation method.We principally use the AHRS scale to evaluate the effectiveness of rTMS on RAH in patients with schizophrenia. Our main hypothesis is that rTMS used under naturalistic conditions, in addition to antipsychotics, would allow a relative improvement of resistant auditory hallucinations assessed by the AHRS scale between baseline and end of treatment in patients with schizophrenia.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 24 Jul 2024
- Start date
- 11 Jul 2022
- Primary completion date
- Jul 2027
- Lead sponsor
- Dominique JANUEL
- Diseases
- Schizophrenia
- NCT number
- NCT06599372
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 11 Jul 2022 to the primary completion date, Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have a contraindication to MST: intracranial foreign body, unstabilized epilepsy, cochlear implant
- Presence of an unstabilized medical condition
Age
- Pregnant woman (Women of childbearing age without effective contraception)
Other
- Current or less than one month old engagement in another research protocol
- A person who is subject to a safeguard of justice measure
- An adult under curatorship
- Minor patients with mental health problems
- Pregnant or breastfeeding women
- A person in a social fragility (Persons deprived of liberty by a judicial or administrative decision, hospitalized persons)
- Persons incapable or unable to give consent
Who the study is looking for
- Patient over 18 years of age
- Patient diagnosed with schizophrenia according to DSM-V criteria (Diagnostic and Statistical Manual of Mental Disorder V5, 2013)
- Presence of auditory hallucinations: Resistant auditory hallucinations: resistance to treatment with 2 different well-conducted antipsychotics.
- Patient agreeing to participate in the study and having signed an informed consent
- Patient with French language skills
- Affiliation to a social security system
- Women of childbearing age must be on contraception and have a negative pregnancy test (βHCG)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Etablissement Public de Santé de Ville-Evrard Coordinator of this site? Confirm its status | Neuilly-sur-Marne | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.