NCT06599463Completed
Efficacy Assessment of Lenvatinib Associated with Pembrolizumab in Metastatic Endometrial Cancer: a French Multicentric Retrospective Early Access Program-based Study
Source: ClinicalTrials.gov · Last updated 20 Mar 2025
Brief summary (registry, in English)
LARENA is a multicentric retrospective study (secondary use of data) of consecutive patients prospectively registered in the lenvatinib plus pembrolizumab French early access program (Temporary Authorisation for Use). The source of data will be the patient's medical file. We will manually review all files of the participating centers.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 351 (actual)
- First submitted
- 11 Sept 2024
- Start date
- Aug 2024
- Primary completion date
- Feb 2025
- Lead sponsor
- ARCAGY/ GINECO GROUP
- Diseases
- Endometrial cancer
- NCT number
- NCT06599463
What you commit to
- Study type: Observational
- Participants enrolled: 351
- From Aug 2024 to the primary completion date, Feb 2025
- 24 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients who refuse the collection and use of their personal data in the course of this research.
Who the study is looking for
- Patients having received at least one dose of lenvatinib plus pembrolizumab in the context of the French early access program (Temporary Authorisation for Use) approved by the French Health Autority.
- Patients with advanced or recurrent endometrial cancer whose disease is progressing during or following prior platinum-based chemotherapy at any stage and who are not eligible for curative surgery or radiotherapy, according to the French early access program (Temporary Authorisation for Use) approved by the French Health Autority criteria.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (24)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ICO Paul Papin Coordinator of this site? Confirm its status | Angers | France | Unknown status |
| Sainte Catherine - Institut du Cancer Avignon Coordinator of this site? Confirm its status | Avignon | France | Unknown status |
| Chu Jean Minjoz Coordinator of this site? Confirm its status | Besançon | France | Unknown status |
| ICONE Coordinator of this site? Confirm its status | Bezannes | France | Unknown status |
| Clinique Tivoli Coordinator of this site? Confirm its status | Bordeaux | France | Unknown status |
| Centre François Baclesse Coordinator of this site? Confirm its status | Caen | France | Unknown status |
| Centre Hospitalier William Morey Coordinator of this site? Confirm its status | Chalon-sur-Saône | France | Unknown status |
| Centre Jean Perrin Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| Centre Georges François Leclerc Coordinator of this site? Confirm its status | Dijon | France | Unknown status |
| CHU de DIJON Coordinator of this site? Confirm its status | Dijon | France | Unknown status |
| Centre Leon Berard Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| Institut Paoli-Calmettes Coordinator of this site? Confirm its status | Marseille | France | Unknown status |
| ICM Val d'Aurelle Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| Hopital Européen George Pompidou Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Centre Cario HPCA Coordinator of this site? Confirm its status | Plérin | France | Unknown status |
| CHU de Poitiers - Hôpital de la Milétrie Coordinator of this site? Confirm its status | Poitiers | France | Unknown status |
| CHI de Cornouaille Coordinator of this site? Confirm its status | Quimper | France | Unknown status |
| Centre Eugène Marquis Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| Institut Curie Coordinator of this site? Confirm its status | Saint-Cloud | France | Unknown status |
| CHU Saint-Etienne - Hôpital Bellevue Coordinator of this site? Confirm its status | Saint-Etienne | France | Unknown status |
| ICANS Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| Oncopole Claudius Regaud IUCT ONCOPOLE Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
| CHU Tours Hôpital Bretonneau Coordinator of this site? Confirm its status | Tours | France | Unknown status |
| Centre Hospitalier de Valence Coordinator of this site? Confirm its status | Valence | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.