NCT06601738Completed
Isometric and Dynamic Handgrip Training Effects on Hypertension
Effects Of Isometrics and Dynamic Handgrip Exercise Training On Cardiovascular Parameters In Hypertensive Patients
Source: ClinicalTrials.gov · Last updated 15 Jun 2025
Brief summary (registry, in English)
Essential hypertension accounts for 13 percent of total deaths worldwide, accounting for one of the major risk factors. Hypertension (high blood pressure) is when the pressure in your blood vessels is too high (140/90 mmHg or higher). Dynamic exercises, sustained hand grip contractions elicit lower systolic blood pressure and heart rate responses. So for patients undergoing exercise therapy, low intensity isometric exercises are preferable. Significant reduction is seen in mean arterial blood pressure and systolic blood pressure in individuals conducting isometric for 8 weeks in 30%. The reduction in systolic blood pressure will be clinically significant. The main objective of this study will be to determine the effects of dynamic and isometric handgrip exercise training on cardiovascular parameters in hypertensive patients Grade 1 hypertensive patients are included as per AHA and JNC7 criteria. A sample of 100 hypertensive patients will be recruited and divided into two treatment groups; G1: dynamic exercise in hypertensive patients, and G2: isometric exercise in hypertensive patients. Outcome measure will include systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and pulse pressure. Outcome measures will be assessed at baseline and 2nd and 4th weeks posttreatment.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 16 Sept 2024
- Start date
- 30 Aug 2024
- Primary completion date
- 30 Dec 2024
- Lead sponsor
- Riphah International University
- Diseases
- High blood pressure
- NCT number
- NCT06601738
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 30 Aug 2024 to the primary completion date, 30 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients having hypertension associated due to other diseases.
- Patients having recent hand surgeries, fracture, history of arthritis, carpal tunnel syndrome.
- Patient having history of any symptoms of chest pain.
Other
- Patients having joint problems of wrist, hand fingers, ligament and tendon injuries of hand and fingers.
- Patients having loss of consciousness during physical activity.
Who the study is looking for
- Gender (both)
- Age (30-55 years)
- Grade 1 hypertensive patients as per AHA and JNC7 criteria
Age in the registry: 30 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Riphah Rehabiliation Clinic Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.