NCT06604104Recruiting
Visual Frailty in Ageing
Seeing Through Their Eyes - Towards Defining Visual Frailty in Ageing
Source: ClinicalTrials.gov · Last updated 4 Mar 2026
Brief summary (registry, in English)
The goal of this observational study is to define visual frailty and refine monitoring for an ageing population. It involves piloting a visual frailty assessment tool in a cohort of patients aged 60 and above with a known diagnosis of Age-related Macular Degeneration (AMD) in Princess Alexandra Eye Pavilion (PAEP), Anne Rowling Clinic which is hosting the NHS Low Visual Aid Clinic, or any other NHS Lothian facility treating patients with Age-related Macular Degeneration (AMD). The main questions it aims to answer are: * What is visual frailty and how can it be assessed or predicted in the global ageing population using visual acuity, reading performance, functional status, mental health and systemic co-morbidities? * What is the relationship between visual acuity, reading performance, ocular diagnosis, co-morbidities, mental health, and functional status? Participants will have the following data collected from them from either Princess Alexandra Eye Pavilion, Anne Rowling Clinic which is hosting the NHS Low Visual Aid Clinic, or any other NHS Lothian facility treating patients with Age-related Macular Degeneration (AMD): * Visual acuity (both distance and near) * Reading performance * Functional status * Mental health * Co-morbidities Data will also be collected remotely (by phone call) from both the participants and their carers/relatives about their perceptions of visual frailty. Expert opinion will be sought from optometrists and ophthalmologists about the concept of visual frailty using an online survey.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 20 (estimated)
- First submitted
- 10 Sept 2024
- Start date
- 9 Apr 2025
- Primary completion date
- 11 Jan 2027
- Lead sponsor
- University of Edinburgh
- Diseases
- Macular degeneration
- NCT number
- NCT06604104
What you commit to
- Study type: Observational
- Planned participants: 20
- From 9 Apr 2025 to the primary completion date, 11 Jan 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants who have undergone invasive ocular surgery like cataract extraction in their previous visit.
Other
- Participants who cannot speak and read English language will not be included in this pilot study. However, non-English speakers will be included in the future together with interpreters at the validation phase of the developed tool.
- The potential participants who fail to provide or do not provide informed consent will not be included in the study.
Who the study is looking for
- Participants should be residents of Scotland aged 60 years and above with a known diagnosis of advanced AMD.
- The patients should be receiving treatment from Princess Alexandra Eye Pavilion (PAEP) for at least 6 months and should be responding positively to the treatment. This is to rule out poor results due to either not receiving medication or non-compliance.
- The participants should be able to provide informed consent before taking part in the study.
Age in the registry: 60 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Princess Alexandra Eye Pavilion Coordinator of this site? Confirm its status | Edinburgh | United Kingdom | Not yet recruiting |
| Anne Rowling Clinic Coordinator of this site? Confirm its status | Edinburgh | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.